
Innovations in Microfluidics 2024: Rapid Prototyping, 3D-Printing
Date: Monday, 6 May 2024 to Tuesday, 7 May 2024
Location: Ann Arbor, Michigan
Confirmed Speakers

Albert Folch
Professor of Bioengineering, University of Washington -- Conference Chairperson

Cory Lambertson, General Manager Americas, ASIGA

Gregory Nordin
Professor, Brigham Young University

Joseph Potkay, Research Assistant Professor, University of Michigan, Clinical Research Engineer, VA Ann Arbor Healthcare System

Noah Malmstadt
Professor, Mork Family Dept. of Chemical Engineering & Materials Science, University of Southern California

Ryan Sochol, Associate Professor, University of Maryland, College Park

Tyler Ray, Professor, University of Hawaii at Manoa

Amar Basu, Professor, Electrical and Computer Engineering, Wayne State University

Daniel Hayes, Stuart B. Padnos Professor of Breast Cancer Research, University of Michigan Rogel Cancer Center

Ian Papautsky, Richard and Loan Hill Professor of Bioengineering, Co-Director, NSF Center for Advanced Design & Manufacturing of Integrated Microfluidics, University of Illinois at Chicago

Leanna Levine, Founder & CEO, ALine, Inc.

Riya Aggarwal, Student Researcher, Potkay Laboratory, University of Michigan - Ann Arbor

Shuichi Takayama, Professor, Georgia Research Alliance Eminent Scholar,
Georgia Institute of Technology & Emory University School of Medicine

Vivek Rajasenan, PhD Candidate, Di Carlo Laboratory, UCLA

Bonnie Gray
Professor of Engineering Science, Simon Fraser University

David Juncker
Professor and Chair, McGill University

Jianping Fu, Professor, Mechanical Engineering, Biomedical Engineering, Cell & Developmental Biology, University of Michigan-Ann Arbor

Mark Burns, T. C. Chang Professor of Engineering, University of Michigan

Robbyn Anand, Associate Professor, Iowa State University

Sunitha Nagrath
Professor of Chemical Engineering and Biomedical Engineering, University of Michigan-Ann Arbor
Innovations in Microfluidics 2024: Rapid Prototyping, 3D-Printing
SelectBIO is delighted to welcome you to Ann Arbor, Michigan to the Innovations in Microfluidics 2024 Conference to be held May 6-7, 2024.
The goal of choosing Ann Arbor, Michigan is to bring the conference in close proximity to the world-class institution which is the University of Michigan with its top-tier faculty and extensive scientific research. The conference seeks to benefit from researchers from the University of Michigan engaging with the conference participants for scientific discussions and networking.
SelectBIO is honored to welcome Professor Dr. Albert Folch, Professor of Bioengineering at the University of Washington, as Conference Chairperson.
SelectBIO welcomes academics and industry participants to engage at this conference both via scientific presentations, exhibits, sponsored talks, technology spotlight presentations and networking over the course of the 2-day conference held onsite.
Call for Posters
Agenda Topics
You can also present your research via a poster while attending the meeting. Submit an abstract for consideration now!
Poster Submission Deadline: 01 May 2024
• 3D-Printing of Microfluidics: Technologies, Methodologies and Tools
• 3D-Tissues
• BioEngineering Approaches for Building Microphysiological Systems/Organs-on-a-Chip
• Building 3D-Structures On-Board Microfluidics Devices: Technologies and Application Areas
• Low-Cost POC Microfluidics Devices for Deployment Worldwide
• Materials for 3D-Printing of Microfluidics Devices
• PDMS and Other Materials for Generating Microfluidics Devices
• Rapid Prototyping in the Microfluidics Field
Sponsorship and Exhibition Opportunities
Jeff Fan
Exhibition Manager - SelectBIO
E-mail: Jeff@selectbioconferences.com
3 for 2 Offer on Delegate Registrations
SelectBIO are offering 3 Delegate Registrations for the price of 2 on all delegate passes. To take advantage of this offer, please contact us by email, phone or click the Contact Us button below. Looking for more than 3 Delegate Passes? Contact us for more information on our special rates for large groups.
Any questions or assistance during registration, please call us at: +1 (510) 857-4865 or e-mail us at: Contact SelectBIO
Gold Sponsors
Exhibitors
Sponsorship and Exhibition Opportunities
If you require any information about exhibiting or sponsoring at one of our events please contact Jeff Fan using the information below:
Jeff Fan, Exhibition Manager
Email: jeff@selectbioconferences.com
Telephone: +1-510-857-4865
Why exhibit at a SELECTBIO show?
Specialists: SELECTBIO doesn't organise conferences in shipping, accountancy, textiles etc. – just drug discovery and the life sciences. Many of our staff have bioscience qualifications and many years of experience. So, we speak your language and understand your needs.
Superior Customer Service: Our sales team will take care of you with specialist advice and customised packages. We don’t forget you after you sign on the bottom line either as our customer service dept. will alert you to all the things you need to think about up to and during the event itself.
Networking: Pre-Event, During and Post-Event you can communicate electronically with all other attendees either using our U-NETWORK system from your PC or via our exclusive new app
Free Lead Retrieval System: Why pay a small fortune for a third party system? SELECTBIO empower you to do this yourself with the badge scanner built into our new app using your smartphone or tablet.
Innovations in Microfluidics 2024: Rapid Prototyping, 3D-Printing 2024 Conference Venue
SelectBIO is pleased to host this Innovations in Microfluidics 2024 Conference at the Hilton Garden Inn -- Ann Arbor, Michigan.
The proximity to the University of Michigan-Ann Arbor enables engagement with the academics at the University and ensures an excellent trip to facilitate scientific exchange and networking.
Hilton Garden Inn Ann Arbor
1401 Briarwood Circle
Ann Arbor, Michigan, 48108
Telephone +1-734-327-6400
SelectBIO has negotiated discounted hotel room pricing for conference attendees at the Hilton Garden Inn-Ann Arbor:
Single Room 179 USD per night
This rate includes internet in the room + local taxes and fees are extra
To make your Hotel Reservations Online:




For any hotel reservation-related issues, or if you need any help with hotel bookings, please contact:
Jeff Fan
Events Manager, SelectBIO
E-mail: Jeff@selectbioconferences.com
SelectBIO has NOT authorized ANY third party company to assist in hotel bookings or reservations for the conference. Please do NOT do business with any third party companies. If in doubt, please contact Jeff Fan immediately to clarify.
Register for this conference and also participate in the Following Co-Located Events at no extra charge:
Training Courses
3D-Printing in Microfluidics
May 5, 2024 from 18:00 - 21:00 in the Michigan Huron Room

Noah Malmstadt, Professor of Chemical Engineering and Materials Science, University of Southern California
3D printing has been gaining popularity as a method for rapidly producing microfluidic devices with complex channel structures routed in three dimensions
This workshop will cover:
Mechanisms of 3D printing techniques as applied to microfluidic fabrication,
The state of the art of commercially available solutions for microfluidic printing
Applications and limitations of 3D-printed microfluidic systems
How emerging and future technologies will improve the potential of 3D printing as a microfluidic fabrication tool
If you would like to submit a proposal for an oral or poster presentation at this meeting, please fill out the form below required for your submission.
Successful applicants will be provided with all necessary information.
Abstract Content:
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Written in English
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Written in the third person
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Include title, name(s) and affiliation(s) of the authors
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Between 100 - 200 words
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Suitable for direct publication in the proceedings pack and on the website
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Related to the subject of the conference
Agenda Topics
• 3D-Printing of Microfluidics: Technologies, Methodologies and Tools
• 3D-Tissues
• BioEngineering Approaches for Building Microphysiological Systems/Organs-on-a-Chip
• Building 3D-Structures On-Board Microfluidics Devices: Technologies and Application Areas
• Low-Cost POC Microfluidics Devices for Deployment Worldwide
• Materials for 3D-Printing of Microfluidics Devices
• PDMS and Other Materials for Generating Microfluidics Devices
• Rapid Prototyping in the Microfluidics Field
Copyrights
The presenting author/person who submitted the abstract assumes full responsibility of the content of the abstract and we assume that all co-authors are aware of this content. Please note that your biography, summary and abstract may be used on this website and conference materials.
Albert Folch, Professor of Bioengineering, University of Washington

Albert Folch Biographical Sketch
Albert Folch’s lab works at the interface between microfluidics and cancer. He received both his BSc (1989) and PhD (1994) in Physics from the University of Barcelona (UB), Spain, in 1989. During his Ph.D. he was a visiting scientist from 1990–91 at the Lawrence Berkeley Lab working on AFM/STM under Dr. Miquel Salmeron. From 1994–1996, he was a postdoc at MIT developing MEMS under Martin Schmidt (EECS) and Mark Wrighton (Chemistry). In 1997, he joined Mehmet Toner’s lab as a postdoc at Harvard-MGH to apply soft lithography to tissue engineering. He has been at Seattle’s UW BioE since June 2000, where he is now a full Professor, accumulating over 12,000 citations. In 22 years, he has supervised 19 postdocs (16% of whom have reached faculty rank), 36 graduate students (12 Ph.D. students, 25% of whom faculty rank, and 24 M.S. students), and ~43 undergraduates. In 2001 he received an NSF Career Award, and in 2014 he was elected to the AIMBE College of Fellows (Class of 2015). He served on the Advisory Board of Lab on a Chip 2010-2016 and serves on the Editorial Board of Micromachines since 2019. In 2022 he was elected a member of the Institute for Catalan Studies, one of the highest honors bestowed on Catalan scientists. He is the author of 5 books (sole author), including Introduction to BioMEMS (2012, Taylor&Francis), a textbook adopted by >103 departments in 18 countries, and Hidden in Plain Sight (MIT Press, 2022). Since 2007, the lab runs a celebrated outreach art program called BAIT (Bringing Art Into Technology), which has produced seven exhibits, a popular resource gallery of >2,000 free images related to microfluidics and microfabrication, and a YouTube channel that plays microfluidic videos with music which accumulate ~163,000 visits since 2009.
Amar Basu, Professor, Electrical and Computer Engineering, Wayne State University

Amar Basu Biographical Sketch
Amar Basu, Ph.D. is a professor of Electrical and Computer Engineering, with a joint appointment in Biomedical Engineering at Wayne State University. He received the M.S.E. and Ph.D. degrees in Electrical Engineering (Circuits and Microsystems) and the M.S. degree in Biotechnology from the University of Michigan Ann Arbor. Upon graduation, he joined Wayne State University, where he is PI of the Microfluidics and Bioinstrumentation Lab, and director of the Wayne State Nanofabrication Facility. His overall research interests are in building translatable lab-on-a-chip and microelectronic systems for biotech and biomedicine. One trajectory of work is in multiphase microfluidic systems, including droplet-based digital assays, particle and cell sorting, novel sensing methods using interfacial phenomena, and computer vision applied to cytometry. Another trajectory includes wearable sensors for health monitoring, and portable systems for environmental monitoring. He is the lead PI for a grant that will acquire one of the first industry-scale 2 photon nanoscale 3d printing system to North America.
Amar has served as the track chair of Micro and Nanotechnologies at the Society of Laboratory Automation and Screening (SLAS), track chair of microfluidics/emerging sensors in IEEE Sensors and IEEE Transducers. He currently serves on the editorial board of SLAS Technology Journal, and Frontiers in Lab on a Chip Technologies. From 2015-2016 He was a visiting research scientist at Intel Corporation and at the Aston Mass Spectrometry Lab under Prof. Graham Cooks. He was VP of Engineering and Digital Assays at Bioelectronica during entrepreneurial leave in 2017-2019 and continues to work with the company to develop Hypercell computer vision single cell sorting technology. The Hypercell platform won the SLAS best new product award in 2020, and the Innovation Showcase award from the International Society for Advancement of Cytometry (ISAC) in the same year. The TRACE wearable sensor, developed by his lab and being commercialized through TRACE Biometrics, won the poster pitch competition at the 2024 National Insitutes on Aging A2 symposium as the most promising new technology for healthy aging.
Bonnie Gray, Professor of Engineering Science, Simon Fraser University

Bonnie Gray Biographical Sketch
Dr. Bonnie L. Gray is a Professor in the School of Engineering Science (ENSC) at Simon Fraser University (SFU) in Canada, a Fraser Health Authority affiliated researcher, and on the board of the Vancouver Medical Device Development Center (MDDC). Dr. Gray has over 140 peer-reviewed journal and conference publications, and has given more than 25 invited, keynote, and plenary presentations at international conferences, in the areas of novel materials and fabrication techniques for biomedical and microfluidic devices and systems; development of flexible and wearable microfluidic and biosensor technologies; point-of-care instruments; and chip-based biological cell sorting and trapping methods. Dr. Gray is a dedicated mentor and the 2014 recipient of the SFU Dean of Graduate Studies Award for Excellence in Supervision. Dr. Gray was the Chapter Chair for the Vancouver IEEE Electron Devices Society (EDS) from 2007-2017, and organizer of two mini-colloquia in 2012 and 2017. She is on the Editorial Board of the IOP Journal of Micromechanics and Microengineering. She chaired the SPIE Conference on Microfluidics, BioMEMS, & Medical Microsystems from 2014-2024, and has been a member of the Program and/or Organizing Committees for various IEEE conferences, including the IEEE MEMS Conference, the IEEE Nanotechnology Materials and Devices Conference (NMDC), and IEEE NANO. She is also active in IEEE awards committees (IEEE NTC and IEEE EMBS); and EDI initiatives, including the IEEE Women in Electron Devices Committee (WiEDS) and a member of Women of Wearables (WoW).
Cory Lambertson, General Manager Americas, ASIGA

Corey Lambertson Biographical Sketch
Cory Lambertson has over 8 years of experience in additive manufacturing. With starting in the corporate world of additive manufacturing in 2015, Cory found a passion for the Asiga brand of 3D Printers due to the revolutionary changes that they bring to the additive world. Today, Cory is the General Manager of Americas at Asiga, and is based out of Ann Arbor Michigan.
Daniel Hayes, Stuart B. Padnos Professor of Breast Cancer Research, University of Michigan Rogel Cancer Center, United States of America

Daniel Hayes Biographical Sketch
Dr. Hayes received undergraduate, master’s and medical degrees from Indiana University, followed by a residency in internal medicine at the University of Texas Southwestern Medical School/Health Science Center/Parkland Memorial Hospital and a fellowship in medical oncology at Harvard’s Dana Farber Cancer Institute (DFCI). He has led the breast cancer programs at DFCI (1991-1996), Georgetown University’s Lombardi Cancer Center (1996-2001), and the University of Michigan from 2001-2016. Dr. Hayes’ research interests are in the field of experimental therapeutics and cancer biomarkers, especially in breast cancer. His work has been particularly focused on development and validation of cancer biomarker tests, such as HER-2, CA15-3, circulating tumor cells and pharmacogenomic markers. He has been instrumental in establishing international guidelines for the use of tumor biomarker tests, including criteria for their clinical utility. He has served as chair of the SWOG Breast Cancer Translational Medicine Committee, and he was an inaugural member and chaired the American Society of Clinical Oncology (ASCO) Tumor Marker Guidelines Committee. He has been instrumental in the joint ad hoc committees between ASCO and the College of American Pathologists. Dr. Hayes served on the ASCO Board of Directors, and served a 3 year term as President of ASCO from 2016-2018. He is a Fellow of ASCO, a Fellow of the American College of Physicians, a past Komen Scholar, and a member of the Association of American Physicians and of the American Clinical and Climatologic Association. He has been the recipient of the ASCO Gianni Bonadonna Award in breast cancer and the Allen Lichter Visionary Leadership Award in 2021 as well as the Susan G. Komen Brinker Award for Scientific Distinction in Clinical Research in 2023, and has received the Distinguished Alumni Award from the Indiana University Medical School (2024).
David Juncker, Professor and Chair, McGill University

David Juncker Biographical Sketch
David Juncker stayed as a visiting scientist at the National Metrology Institute of Japan in Tsukuba from 1997-98. He conducted his PhD research at the IBM Zurich Research Laboratory from 1999-2002. He then pursued his studies as a Post-doc first at IBM Zurich until 2004, and then one year at the Swiss Federal Institute of Technology in Zurich (ETH). David started as an assistant professor in the Biomedical Engineering Department of McGill University in 2005, was promoted to associate professor with tenure in 2011, and became a full professor in 2016. As of early 2018, David serves as departmental chair of the Biomedical Engineering Department at McGill University.
Dr. Juncker's current interests are in the miniaturization and integration in biology and medicine, which includes the engineering and utilization of novel micro and nanotechnologies for manipulating, stimulating and studying oligonucleotides, proteins, cells, and tissues. The emerging field of nanobiotechnology, in a broad sense, is the most exciting to him, and is also key to tackle some of the major challenges in biology and medicine, for example identifying novel biomarkers for early disease diagnosis and developing low-cost point-of-care diagnostics.
Gregory Nordin, Professor, Brigham Young University

Greg Nordin Biographical Sketch
Professor Greg Nordin joined the faculty of the Electrical & Computer Engineering Department at Brigham Young University in 2005. From 1992 to 2005 he was at The University of Alabama in Huntsville (UAH) where he was the founding director of the university's Nano and Micro Devices Center, which was created as an independent research center by the University of Alabama System Board of Trustees. While director of the center, he created a 7,600 sq. ft. cleanroom facility for nano and microfabricated devices to pursue research activities in photonics, MEMS, microfluidics, and sensors. Prof. Nordin has led numerous large research programs, and has been principal investigator on research grants from government and industry totaling $18M. He is the recipient of the National Science Foundation CAREER award (1996) for promising young faculty, and twice received the UAH Outstanding Researcher Award as well as the UAH Foundation Award for Research and Creative Achievement. Prof. Nordin's current research is focused on developing 3D printing for microfluidic devices and applications. In March 2018 Prof. Nordin gave a TED talk on his group's work, which is available at https://www.youtube.com/watch?v=T122fzOEVYE.
Ian Papautsky, Richard and Loan Hill Professor of Bioengineering, Co-Director, NSF Center for Advanced Design & Manufacturing of Integrated Microfluidics, University of Illinois at Chicago

Ian Paputsky Biographical Sketch
Ian Papautsky is the Richard and Loan Hill Professor in the biomedical engineering department. His lab focuses on using microfluidics to innovate blood analysis. Papautsky was one of the pioneers of the inertial microfluidics technology for label-free isolation and analysis of rare cells. His recent work has focused on applying this approach to the fractionation of blood, as well as capture and subsequent molecular profile analysis of circulating tumor cells for liquid biopsy. Papautsky is also co-director of the National Science Foundation Center for Advanced Design and Manufacturing of Integrated Microfluidics, an industry-university collaborative research center that fosters interactions between academics and businesses in the areas of medical devices, pharmacology, and precision agriculture. Papautsky joined the University of Illinois Chicago in 2016. He has been recognized with many awards and honors, including Ohio Bioscience 30 in Their 30s. He is fellow of the AIMBE and the RSC.
Jianping Fu, Professor, Mechanical Engineering, Biomedical Engineering, Cell & Developmental Biology, University of Michigan-Ann Arbor

Jianping Fu Biographical Sketch
Dr. Jianping Fu is a Professor of Mechanical Engineering, Biomedical Engineering, and Cell & Developmental Biology at the University of Michigan. Dr. Fu’s research focuses on stem cell bioengineering, developmental bioengineering, mechanobiology, and microfluidics. Dr. Fu and his co-workers' research has contributed significantly to the emerging field of "Artificial Embryos", which was selected by the MIT Technology Review as “10 Breakthrough Technologies of 2018”. Dr. Fu is the recipient of the NSF CAREER Award, the BMES-CMBE Rising Star Award, the ACS Analytical Chemistry Young Innovator Award, the Alexander von Humboldt Foundation Friedrich Wilhelm Bessel Research Award, and numerous awards from the University of Michigan. Dr. Fu is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE), the Royal Society of Chemistry (RSC), the American Society of Mechanical Engineers (ASME), the International Academy of Medical and Biological Engineers (IAMBE), and the Biomedical Engineering Society (BMES). Dr. Fu was a member of the International Society for Stem Cell Research (ISSCR) Guidelines Working Group from 2019 to 2021 and is currently a member of the ISSCR Publications Committee. He is a council member of the Biomedical Engineering Society Cellular and Molecular Bioengineering Special Interest Group (BMES CMBE-SIG). Dr. Fu currently serves as the Associate Editor of npj Regenerative Medicine and is an Editorial or Advisory Board Member of Cell Stem Cell, Biophysical Journal, Cell Regeneration, Mechanobiology in Medicine, and Frontiers in Cell and Developmental Biology. Additionally, Dr. Fu is a Founding Member of the Catalysts Program of EMBO Journal.
Joseph Potkay, Research Assistant Professor, University of Michigan, Clinical Research Engineer, VA Ann Arbor Healthcare System

Joe Potkay Biographical Sketch
Dr. Joseph Potkay received his Ph.D. in electrical engineering from the University of Michigan under the direction of MEMS pioneer Dr. Ken Wise in 2006. Since 2006, he has served as a research investigator at the Department of Veterans Affairs with the goal of bringing the huge potential of micro- and nano-technologies to bear on issues critical to the Veteran population. He additionally serves as research assistant professor in the Department of Surgery at the University of Michigan. Dr. Potkay has 45 peer-reviewed publications, four patents, has presented his research at local, national, and international conferences, and has been interviewed by Public Radio, Nature Magazine, and CNN regarding his artificial lung research. He is a senior member of the Institute of Electrical and Electronic Engineers (IEEE), and member of the Engineering in Medicine and Biology Society (EMBS), the American Society for Artificial Internal Organs (ASAIO), and the Extracorporeal Life Support Organization. He serves or has served on the editorial boards of the Micromachines and ASAIO Journals and the EMBC and ASAIO conferences. His artificial lung research has been continuously funded by the Department of Veterans Affairs and NIH since 2007.
Leanna Levine, Founder & CEO, ALine, Inc.

Leanna Levine Biographical Sketch
Dr. Levine, founder of ALine, Inc., is an entrepreneur, technologist, and inventor. She has a unique blend of technical expertise in both bioanalytical science and manufacturing process development. Prior to founding ALine, Dr. Levine developed bioanalytical technology to support life science research. While at Monsanto, her lab led the industry in the application of fluorescence polarization for high throughput screening for novel therapeutics. In 1998 she joined Spectrum Laboratories as Director of Hollow Fiber Manufacture and Product Development. Dr. Levine earned her Ph.D. at Washington University, St. Louis, MO , and her B.S. in Biochemistry and BA in German from the University of Missouri, Columbia, MO. In 2003 she was a visiting scholar at the UCLA Anderson School of Business. In 2000 she was the chair of the Gordon Conference on Bioanalytical Sensors. She is the co-author on a dozen publications, and several patents.
Mark Burns, T. C. Chang Professor of Engineering, University of Michigan

Mark Burns Biographical Sketch
Prof. Mark A. Burns is the T. C. Chang Professor of Engineering and a Professor in both Chemical Engineering and Biomedical Engineering at the University of Michigan. He obtained his MS and PhD degrees in Chemical and Biochemical Engineering from the University of Pennsylvania, and his BS degree from the University of Notre Dame. Prof. Burns has over 350 publications, patents, and presentations. He is a Fellow of the National Academy of Inventors, the American Institute for Chemical Engineers, and the American Institute for Medical and Biological Engineering. He has won numerous awards including the Food, Pharmaceutical, and Bioengineering Division Award from AIChE, and both a Teaching Excellence Award and a Research Excellence Award from the College of Engineering at the University of Michigan. He has also served in a variety of administrative positions at Michigan including Chair of the Chemical Engineering Department, Advisor to the Dean of Engineering, and Executive Director of Mcubed and Research Innovation in the Office of the Vice President for Research.
Noah Malmstadt, Professor, Mork Family Dept. of Chemical Engineering & Materials Science, University of Southern California

Noah Malmstadt Biographical Sketch
Noah Malmstadt is Professor at the University of Southern California. He received a BS in Chemical Engineering from Caltech and a PhD in Bioengineering from the University of Washington. Following postdoctoral work at UCLA, he joined the Mork Family Department of Chemical Engineering and Materials Science at USC in 2007. Malmstadt is the recipient of a 2012 Office of Naval Research Young Investigator award. His research focuses on microfluidic strategies to facilitate material fabrication and biophysical analysis. He has pioneered the integration of ionic liquids as solvents in droplet microreactors and the application of microfluidic systems to synthesizing biomimetic cell membranes. Microfluidic analytical techniques he has developed include methods for measuring the permeability of cell membranes to druglike molecules and techniques for measuring ionic currents through membrane proteins.
Riya Aggarwal, Student Researcher, Potkay Laboratory, University of Michigan - Ann Arbor

Riya Aggarwal Biographical Sketch
Riya Aggarwal is a student researcher at the Potkay Lab at the VA Ann Arbor Healthcare System and the ECLS Lab at the University of Michigan. She will earn her Bachelor of Science in Molecular, Cellular, and Developmental Biology with a Double Minor in Art & Design and Sociology of Health & Medicine from the University of Michigan in May 2024. Her interests and experience lie in artificial bio-nanotechnology research, namely working to create 3D printed microfluidic devices. Riya Aggarwal’s research focuses on formulating hemocompatible UV-resins for the development of biomimetic, microfluidic 3D-printed artificial lungs. She has conducted extensive research in formulations and material testing under Dr. Joseph Potkay, exploring the nonthrombogenic effects of imbuing PDMS-based resin for stereolithography with hydrophilic molecules. Pursuing a career in medicine, Riya Aggarwal is committed to the goal of pushing medicine towards bolstering vulnerable populations, advancing current knowledge, and finding creative solutions to complex problems.
Robbyn Anand, Associate Professor, Iowa State University

Robbyn Anand Biographical Sketch
Robbyn K. Anand is the Suresh Faculty Fellow and Carlyle G. Caldwell Endowed Chair in Chemistry at Iowa State University. Her group has developed methods for circulating tumor cell analysis, electrokinetic enrichment and separation of chemical species within water-in-oil droplets, and more sensitive bioanalysis at arrays of wireless bipolar electrodes. Prof. Anand also founded the Midwest Retreat for Diversity in Chemistry - an annual event aimed at the retention of underrepresented groups in the chemical enterprise.
Ryan Sochol, Associate Professor, University of Maryland, College Park

Ryan Sochol Biographical Sketch
Prof. Ryan D. Sochol is an Associate Professor of Mechanical Engineering within the A. James Clark School of Engineering at the University of Maryland, College Park (UMD). Prof. Sochol received his B.S. from Northwestern University, and both his M.S. and Ph.D. from the University of California, Berkeley. Prior to joining the faculty at UMD, Prof. Sochol served as: (i) an NIH Postdoctoral Trainee within the Harvard-MIT Division of Health Sciences & Technology, Harvard Medical School, and Brigham & Women’s Hospital, (ii) Director of the Micro Mechanical Methods for Biology (M3B) Laboratory Program within the Berkeley Sensor & Actuator Center at UC Berkeley, and (iii) a Visiting Postdoctoral Fellow at the University of Tokyo. In 2019, Prof. Sochol was elected Co-President of the Mid-Atlantic Micro/Nano Alliance. His group received IEEE MEMS Outstanding Student Paper Awards in both 2019 and 2021 and the Springer Nature Best Paper Award (Runner-Up) in 2022. Prof. Sochol received the NSF CAREER Award in 2020 and the Early Career Award from the IOP Journal of Micromechanics and Microengineering in 2021, and was recently honored as an inaugural Rising Star by the journal, Advanced Materials Technologies, in 2023.
Shuichi Takayama, Professor, Georgia Research Alliance Eminent Scholar, and Price Gilbert, Jr. Chair in Regenerative Engineering and Medicine, Georgia Institute of Technology & Emory University School of Medicine

Shu Takayama Biographical Sketch
Prof. Shuichi Takayama’s research interests started with bioorganic synthesis at the University of Tokyo and Scripps Research Institute. Subsequently he pursued postdoctoral studies in bioengineered microsystems at Harvard University as a Leukemia and Lymphoma Society Fellow. He spent 17 years at the University of Michigan in the Biomedical Engineering Department and Macromolecular Science and Engineering Program, then moved to the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory School of Medicine in the summer of 2017. He is an associate editor of Integrative Biology and recipient of the Pioneers of Miniaturization Prize. He is also the Director of the Nakatani RIES Program which promotes international undergraduate student internships between the US and Japan.
Sunitha Nagrath, Professor of Chemical Engineering and Biomedical Engineering, University of Michigan-Ann Arbor

Sunitha Nagrath Biographical Sketch
Dr. Sunitha Nagrath is a Professor of Chemical Engineering and Biomedical Engineering at University of Michigan. Dr. Nagrath received her Ph.D. in 2004 from Rensselaer Polytechnic Institute, Troy, NY in Mechanical Engineering. She did her postdoctoral work at Harvard Medical/Massachusetts General Hospital, Boston, under the mentorship of Dr. Toner. Dr. Nagrath is the leading scientist who designed the MEMS based technology, “CTC-Chip” for the sensitive isolation of circulating tumor cells (CTCs) from the blood of cancer patients. She joined the University of Michigan in 2010 as a tenure track faculty, where she established her laboratory focused on engineering innovative microfluidic devices and nanomaterials for implementing personalized precision medicine via liquid biopsy. Dr. Nagrath’s major focus of research is on understanding cell trafficking in cancer through the isolation, characterization, and study of circulating cells and extracellular vesicles in the peripheral blood of cancer patients. She is a co-director of the Liquid Biopsy Shared Resource at UMICH Comprehensive Cancer Center, where she oversees the services of isolation and characterization of biomarkers and their implementation in clinical studies. She is an elected fellow of AIMBE and received several accolades including, Analytical Chemistry Young Innovator Award, and NIH Director’s New innovator award. Dr. Nagrath is the co-founder and the board member of Labyrinth Biotech, a biotechnology company commercializing some of the technologies that are developed in her lab.
Tyler Ray, Professor, University of Hawaii at Manoa

Tyler Ray Biographical Sketch
Tyler Ray is currently an assistant professor of mechanical engineering at the University of Hawaii at Manoa. He received his BS and MS in mechanical engineering from the University of South Carolina and his PhD in mechanical engineering from the University of California, Santa Barbara. Ray received his postdoctoral training as a fellow at Northwestern University in the Rogers Research Group. Ray is a recipient of the National Science Foundation CAREER award (2023) and is currently an NIH COBRE research project leader. Professor Ray’s research focus is at the intersection of materials science, additive manufacturing, and wearable sensors.
Vivek Rajasenan, PhD Candidate, Di Carlo Laboratory, UCLA

Vivek Rajasenan Biographical Sketch
Vivek Rajasenan is a Graduate Student at the Di Carlo Lab at the University of California Los Angeles (UCLA). He received his undergraduate degree in Automotive Engineering and is currently pursuing a PhD in Mechanical Engineering. His research focuses on 3d printed microfluidics with applications in inertial microfluidics and complex particle and functional fiber fabrication.
6 May 2024
08:00
Conference Registration and Materials Pick-Up + Coffee and Pastries in the Exhibit Hall
Michigan Huron Room
6 May 2024
09:00
Albert Folch, Professor of Bioengineering, University of Washington, United States of America and Sunitha Nagrath, Professor Chemical Engineering, University of Michigan
Welcome and Introduction by Conference Chairpersons -- Scope of the Conference and Topics Covered
Michigan Huron Room
6 May 2024
09:10
Session Title: 3D-Printing of Microfluidics
Michigan Huron Room
6 May 2024
09:15

Gregory Nordin, Professor, Brigham Young University, United States of America
High Resolution Negative Space 3D Printing for Microfluidics
While there is great interest in 3D printing for microfluidic device fabrication, a main challenge has been to achieve feature sizes that are in the truly microfluidic regime (<100 μm). A key issue is that microfluidic devices are comprised primarily of negative space features, which therefore dominate 3D printing resolution requirements, as compared to positive space features that are typical for many other 3D printing applications. Consequently, we have developed our own stereolithographic 3D printers and materials that are specifically tailored to meet these needs. We have shown 3D printed channels as small as 18 μm x 20 μm, and have recently reduced this to 2 μm x 2 μm. We have also developed active elements such as valves and pumps with the smallest valves having an active area of only 15 μm x 15 μm. In this presentation we discuss how such results are achieved and demonstrate miniaturized components including small (<1mm^3) fast (~1 ms) mixers and isoporous membranes with 7 μm pores. We also demonstrate integrated 3D printed devices such as for controllable cell chemotaxis. Advances in negative space 3D printing open the door to replacing expensive cleanroom fabrication processes with 3D printing, with the additional advantage of fast (~5-15 minute), parallel fabrication of many devices in a single print run due to their small size.
Michigan Huron Room
6 May 2024
10:00

Noah Malmstadt, Professor, Mork Family Dept. of Chemical Engineering & Materials Science, University of Southern California, United States of America
Modular Design Workflows for 3D Printed Microfluidics
3D printing brings with it a plethora of advantages for microfluidic applications. Principle among these are rapid prototyping, iterative design, and the ability to avoid the cost and overhead of cleanrooms. However, there is also an inherent advantage in being able to design and build devices in a truly three-dimensional, rather than layer-by-layer, geometry. One simple domain in which the advantages of true 3D routing are clear is in mixing. Control over a 3D geometry allows for multiple complex mixing configurations--herringbones, relamination mixers, chaotic advection--to be trivially constructed and recombined.
We have used these principles of 3D design to construct devices and systems for bioanalytical assays, for manufacturing biomaterials, and for industrial-scale manufacturing of novel materials. This talk will examine all of these applications and the manner in which 3d-centric microfluidic design can enable them.
Michigan Huron Room
6 May 2024
10:30

Joseph Potkay, Research Assistant Professor, University of Michigan, Clinical Research Engineer, VA Ann Arbor Healthcare System, United States of America
A High Resolution, SLA PDMS Resin and its Application in Microfluidic Organ Models
This presentation will cover our progress toward developing and characterizing a high resolution and biocompatible polydimethylsiloxane SLA 3D printing resin and its use to create various microfluidic structures including microfluidic artificial lungs.
Exhibit Hall
6 May 2024
11:00
Mid-Morning Coffee Break and Networking in the Exhibit Hall
Michigan Huron Room
6 May 2024
11:30

Bonnie Gray, Professor of Engineering Science, Simon Fraser University, Canada
Additive Manufacturing for Microfluidic and Wearable Sensor Systems
We are surrounded by sensors in our daily lives. These (usually) small, inobtrusive devices constantly capture data about our environment, and what we see, hear, and do. Sensors form the foundation for analysis systems and are an integral part of every closed-form system. Many sensors seek to provide more continuity for health and well-being via constant monitoring of important health parameters. Similarly, other sensors seek to address the health of other systems, such as preventing failures in the power grid. Sensors as discrete components may be difficult to integrate into low-profile systems, such as textile-based systems, for development of smart clothing. These and other sensors systems could benefit from 3D printing or other additive manufacturing methods, via the integration of conventional printing materials with new functional (e.g., sensing or actuating) printed materials. Sensors could thus be easily tailored and printed to individual needs and more easily integrated with other printed components. This presentation focuses on development of wearable and other printed sensors that are designed directly on textiles, or fabricated using 3D printing methods for easier integration with fluidic housings. We discuss the current state-of-the-art, and present examples of integrated textile-based and printing-based sensors. We investigate how advances in flexible devices and systems (electronics, sensors, actuators, microfluidics) and additive manufacturing (e.g., printing) can be adapted to low-profile, non-obtrusive, and personalized sensor systems.
Michigan Huron Room
6 May 2024
12:00

Leanna Levine, Founder & CEO, ALine, Inc., United States of America
Integration and DFM for Microfluidics
Most microfluidic cartridges require integration of mixed materials and components to create the complete functional product architecture. This talk will address the key considerations for DFX while leveraging a range of prototyping techniques including 3D printing, CNC machining, Injection molding and Laminate Fluid Circuit Technology, to position a product for transfer to scale up with high volume manufacturing techniques.
Exhibit Hall
6 May 2024
12:30
Networking Buffet Lunch in the Exhibit Hall -- Networking with Colleagues, Engage with Exhibitors and View Posters
Michigan Huron Room
6 May 2024
13:30

Amar Basu, Professor, Electrical and Computer Engineering, Wayne State University, United States of America
Rapid Micromolding of Sub-100 Micron Microfluidic Devices Using an 8K Resin 3D Printer
Microfluidics relies on the ability to manufacture sub-100 micrometer fluidic channels. Conventional lithographic methods provide high resolution but have turnaround time of several days, while rapid prototyping methods (e.g., laser cutters, craft cutters, fused deposition modeling) have feature sizes of several hundred microns or more. This talk describes a single-day process for fabricating sub-100 µm channels, leveraging a low-cost 8K digital light projection (DLP) 3D resin printer. The process can create microchannels with 44 µm lateral resolution and 25 µm height, posts as small as 400 µm, aspect ratio up to 7, structures with varying z-height, integrated reservoirs for fluidic connections, and a built-in tray for casting. This talk will cover the key process steps (mold printing, post-treatment, and casting polydimethylsiloxane (PDMS) elastomer) and discusses strategies to obtain robust structures, prevent mold warpage, facilitate curing and removal of PDMS during molding, and recycle the solvents used in the process. This process provides a balance between resolution, turnaround time, and cost (~USD 5 for a 2 × 5 × 0.5 cm3 chip) that may be useful for many microfluidics labs.
Michigan Huron Room
6 May 2024
14:00

Ryan Sochol, Associate Professor, University of Maryland, College Park, United States of America
3D-Printed Microfluidic Circuitry via Alternative Additive Manufacturing Strategies
Over the past decade, researchers have demonstrated that additive manufacturing—or “three-dimensional (3D) printing”—approaches provide powerful means for achieving integrated microfluidic circuits and systems. Although the majority of developments in the area of 3D-printed microfluidic circuitry have relied on mesoscale “vat photopolymerization” techniques, such as “stereolithography”, there are a wide range of additive manufacturing approaches that offer utility for microfluidic circuit design, fabrication, and integration. In this talk, Prof. Ryan D. Sochol will discuss how his Bioinspired Advanced Manufacturing (BAM) Laboratory is leveraging the capabilities of alternative additive manufacturing technologies—namely “PolyJet 3D Printing” and “Two-Photon Direct Laser Writing”—to realize 3D-printed microfluidic circuits for soft robotic applications… including a soft robotic “hand” that plays Nintendo.
Michigan Huron Room
6 May 2024
14:30

Xudong Fan, Richard A. Auhll Endowed Professor of Engineering and Professor, Biomedical Engineering, University of Michigan
Weishu Wu, PhD Candidate in the Laboratory of Prof Xudong Fan
Antigen-Independent Single-Cell Phenotyping Using Biolasers
In this talk we will present our work on deep learning-assisted biolaser platform that examines the intracellular environment and is capable of performing cell classification without depending on labeling specific proteins on the cells. We verified our system on detecting circulating tumor cells from white blood cells (WBCs) with high accuracy.
Michigan Huron Room
6 May 2024
15:00

Mark Burns, T. C. Chang Professor of Engineering, University of Michigan, United States of America
Biochemical Assays in Variable Height Microfluidic Devices
Processing of solid particles in 3D-printed fluidic channels has the potential to expand the application space of microfluidic systems. As an example, selective binding of proteins, DNA, and other biological substances is used in assays to detect pathogens, diagnose disease, and guide patient treatment. The capture of these substances can take place in a bulk liquid phase, which is generally simpler, or on a solid surface, which provides the benefit of straightforward two-dimensional result interpretation. We combine these two techniques to achieve the best of both worlds. We use an antibody sandwich assay with the capture antibody immobilized on the solid surface of microbeads, each of which has a specific diameter corresponding to one protein in a multiplexed adsorption assay. The beads are then introduced into a microfluidic channel with varying heights, allowing each bead size to become trapped at a distinct location. This method effectively transforms a three-dimensional suspension into a two-dimensional layout, simplifying the reading of binding results. The channel is currently constructed using a variable etch of a glass substrate in hydrofluoric acid but we hope to use other techniques such as 3D printing to produce these chips. One printing technique we have developed, dual-wavelength stereolithography, could eventually fulfill this goal but the current resolution is too low.
Michigan Huron Room
6 May 2024
15:30

Cory Lambertson, General Manager Americas, ASIGA, United States of America
ASIGA Advancing 3D Printed Microfluidics
ASIGA is a leader in reliable and precise DLP 3D Printers. In this talk we will show you how to leverage our open material system and voxel-level control over all parameters in our 3D printers to create cutting edge Microfluidic Chips.
Michigan Huron Room
6 May 2024
16:00

Tyler Ray, Professor, University of Hawaii at Manoa, United States of America
3D-Printed Epidermal Microfluidic Systems
An emerging class of wearable devices integrates microfluidic lab-on-chip designs with low-modulus materials, colorimetric assays, and electrochemical sensors to support the real-time, non-invasive analysis of sweat. Such skin-interfaced microfluidic systems offer powerful capabilities for personalized assessment of health, nutrition, and wellness through the non-invasive, real-time analysis of sweat. Initially simple systems of microfluidic channels, current devices comprise sophisticated networks channels, valves, and reservoirs with some embodiments employing multilayer design strategies. While these platforms exhibit powerful analytical capabilities, device fabrication requires time, labor, and resource-intensive cleanroom processing, which restricts the device design space (2D) and elongates the development time. Additive manufacturing processes, particularly stereolithography (SLA)-based printing, offer powerful pathways for overcoming these limitations by providing significant reductions in prototype development cost and cycle time while substantially expanding device capabilities with fully 3D device designs. Here, we present a simplified 3D-printing prototyping process to fabricate flexible, stretchable, epidermal microfluidic devices (‘3D-epifluidics’). Reducing fabrication time to [O]min, this approach enables the integration of spatially-engineered features including 3D-structured passive capillary valves, monolithic channels, and reservoirs with spatially-graded geometries. With geometric features comparable to established epifluidic devices (channels >50 µm), benchtop and on-body testing validate the performance of 3D-epifluidic devices.
Michigan Huron Room
6 May 2024
16:30

Shuichi Takayama, Professor, Georgia Research Alliance Eminent Scholar, and Price Gilbert, Jr. Chair in Regenerative Engineering and Medicine, Georgia Institute of Technology & Emory University School of Medicine, United States of America
High-Throughput Lung Microphysiological Systems
There is a need to better understand lung disease, accelerate drug discovery, and better predict human clinical trial outcomes and individualized drug responses. This presentation will describe efforts to develop microphysiological systems (MPSs) to accomplish this goal. Specific topics include the first microfluidic lung-on-a-chip developed at Michigan. A Transwell-96 based air-blood barriers that can be coupled with automated flow cytometry. And a 384 well format assay using lung Organoids with Reversed Biopolarity (lung-ORBs). Specific applications include single-ORB based high-throughput assays of SARS-CoV-2 infection and therapeutics, neutrophilic inflammation studies, and analyzing the injurious effects of fluid mechanical effects associated with lung stethoscope sounds.
Exhibit Hall
6 May 2024
17:00
Beer and Wine Networking Reception
6 May 2024
20:30
Close of Day 1 of the Conference
Exhibit Hall
7 May 2024
08:00
Morning Coffee, Pastries and Networking in the Exhibit Hall
Michigan Huron Room
7 May 2024
08:30

Ray Eby, Central US Accounts Manager, Particle Metrix, Inc., United States of America
Latest Developments in ZetaView® NTA Platform
Particle Metrix continues to innovate for the benefit of analyzing biological nanoparticles, and our latest developed will be discussed. Fluorescence NTA methods including our new colocalization NTA capability will be featured.
Michigan Huron Room
7 May 2024
09:00

Robbyn Anand, Associate Professor, Iowa State University, United States of America
Expanding the Droplet-Microfluidics Toolkit with Electrokinetics
Droplet-based techniques have had a profound impact in biotechnology, owing to an ability to perform rapid and massively parallel reactions in minute fluid volumes. However, once droplets are formed, their composition can be altered through limited functions including the addition of reagents through droplet merging, which increases droplet volume, and through in-droplet mixing. Further, while droplet contents can be measured through, there remains a need for more versatile methods to probe droplets without significantly altering their contents. In this presentation, we describe a suite of in-droplet electrokinetic methods including de-mixing, mobility-based separations, desalting, and “salting”. Finally, we will share initial results for the measurement of the ionic content of droplets.
Michigan Huron Room
7 May 2024
09:30

Sunitha Nagrath, Professor of Chemical Engineering and Biomedical Engineering, University of Michigan-Ann Arbor, United States of America
Micro Innovations Defining the New Frontiers of Liquid Biopsy
Microfluidic technologies were always at the forefront of innovations in liquid biopsies. There were several corner stone microfluidic technologies that enabled sensitive and yet specific identification of blood-based biomarkers. The confluence of technology advancement and rapid developments in molecular characterization techniques pushed the boundaries of liquid biopsies thus enhancing the clinical utility of blood biopsies. Several such key enabling technologies will be presented. How isolation of circulating tumor cells using novel microfluidic technologies can enable precision diagnostics will be demonstrated with the example clinical case studies.
Exhibit Hall
7 May 2024
10:00
Mid-Morning Coffee Break and Networking in the Exhibit Hall
Michigan Huron Room
7 May 2024
10:30

David Juncker, Professor and Chair, McGill University, Canada
Custom and Mass Manufacturing of High Resolution Microfluidics by Low Cost SLA 3D Printing
I will present our work on stereolithography DLP and LCD 3D printing for microfluidics and notably how it elevated and transformed capillaric circuits (CC); CCs are structurally-encoded pre-programmed capillary microfluidics operating without moving part, peripherals nor computer, and powered by the free surface energy of paper. Capillaric circuits are hierarchically built from basic elements such as microchannels, resistances, pumps, valves (incl. stop-, trigger-, retention-, retention burst-, and domino-valves) and more complex sub-systems such as microfluidic chain reactions for scalable, algorithmic liquid handling operations. The progression from replica molding to digital manufacturing – i.e. from a digital file to functional device thanks to new hydrophilic inks – will be illustrated with various designs, notably the ELISA chip for point-of-care diagnostics. The potential of ultra-low cost LCD 3D printers and custom inks for microfluidics will be illustrated via microfluidic mixers, active valves, ELISA chips, and by mass manufacturing thousands of organ-on-chip devices in a single run. SLA 3D printing together with tailored inks pave the way for high-resolution distributed manufacturing of ready-to-use microfluidic systems (e.g. CCs with structurally encoded algorithms ) anywhere, by anyone who can spare US$300 to buy an LCD 3D printer.
Michigan Huron Room
7 May 2024
11:00

Jianping Fu, Professor, Mechanical Engineering, Biomedical Engineering, Cell & Developmental Biology, University of Michigan-Ann Arbor, United States of America
Bioengineered Human Embryo and Organ Models
Early human development remains mysterious and difficult to study. Recent advances in developmental biology, stem cell biology, and bioengineering have contributed to a significant interest in constructing controllable, stem cell-based models of human embryo and organs (embryoids / organoids). The controllability and reproducibility of these human development models, coupled with the ease of genetically modifying stem cell lines, the ability to manipulate culture conditions and the simplicity of live imaging, make them robust and attractive systems to disentangle cellular behaviors and signaling interactions that drive human development. In this talk, I will describe our effort in using human pluripotent stem cells (hPSCs) and bioengineering tools to develop controllable models of the peri-implantation embryonic development and early neural development. The peri-implantation human embryoids recapitulate early post-implantation developmental landmarks successively, including amniotic cavity formation, amniotic ectoderm-epiblast patterning, primordial germ cell specification, development of the primitive streak, and yolk sac formation. I will further discuss an hPSC-based, microfluidic neural tube-like structure (or µNTLS), whose development recapitulates some critical aspects of neural patterning in both brain and spinal cord regions and along both rostral-caudal and dorsal-ventral axes. The µNTLS is further utilized for studying development of different neuronal lineages, revealing pre-patterning of axial identities of neural crest progenitors and functional roles of neuromesodermal progenitors and caudal gene CDX2 in spinal cord and trunk neural crest development. We have further developed dorsal-ventral patterned, microfluidic forebrain-like structures (µFBLS) with spatially segregated dorsal and ventral regions and layered apicobasal cellular organizations that mimic human embryonic brain development in pallium and subpallium areas, respectively. Together, both µNTLS and µFBLS offer 3D lumenal tissue architectures with an in vivo-like spatiotemporal cell differentiation and organization, useful for studying human neurodevelopment and disease.
Michigan Huron Room
7 May 2024
11:30

Albert Folch, Professor of Bioengineering, University of Washington, United States of America
Fluidtronics: 3D-Printed Microfluidic Transistors and Higher-Complexity Circuits
Microfluidic automation has become an essential technology in fields such as genomics, proteomics, pharmaceutical testing, cell biology, tissue engineering, and organs-on-chips. However, as the experimental complexity increases, the complexity of the off-chip controls also increases. Paradoxically, a lab-on-a-chip becomes a less efficient “chip in a lab”. To address this “chip-in-a-lab” paradox, microfluidic researchers have borrowed from microelectronics the powerful formalism of microfluidic logic gates (µFLGs), typically built with PDMS valves that act as “microfluidic transistors”. However, the manufacturing challenges of soft-lithography techniques (e.g., cost, labor, expertise) significantly limit the large-scale democratization of microfluidic transistor technology among interested researchers and users. We describe stereolithography (SLA) resins that allow for emulating the elasticity properties of PDMS and SLA-print microfluidic transistors and analog fluidic amplifiers with characteristics similar to those built PDMS transistors. This work is the first step towards advanced-manufactured autonomous microfluidic transistor-based circuits and integrated controls that we call “Fluidtronics."
Exhibit Hall
7 May 2024
12:00
Networking Buffet Lunch in the Exhibit Hall -- Networking with Colleagues, Engage with Exhibitors and View Posters
Michigan Huron Room
7 May 2024
12:50
Session Title: Liquid Biopsy 2024 - A Snapshot
Michigan Huron Room
7 May 2024
12:55
Session Chairperson: Professor Sunitha Nagrath, University of Michigan-Ann Arbor
Michigan Huron Room
7 May 2024
13:00

Daniel Hayes, Stuart B. Padnos Professor of Breast Cancer Research, University of Michigan Rogel Cancer Center, United States of America
Taking a Liquid Biopsy from Lab to Clinic: What It Takes to Get Ready for Prime Time
A tumor biomarker liquid biopsy test, is not just an assay for circulating proteins, tumor cells, or cell free DNA. Rather, it is a precisely developed assay that has high analytical validity and clinical utility for a specific use context. Clinical utility requires consideration of several factors and the generation of high levels of evidence that use of the assay, compared to not having the results at all, improves patient outcomes – preferably either quality or quantity of life. These issues will be discussed in the presentation.
Michigan Huron Room
7 May 2024
13:30

Ian Papautsky, Richard and Loan Hill Professor of Bioengineering, Co-Director, NSF Center for Advanced Design & Manufacturing of Integrated Microfluidics, University of Illinois at Chicago, United States of America
Whole Blood Microfluidics
Microfluidic devices based on inertial microfluidics have attracted considerable attention for applications in blood fractionation and liquid biopsy due to their label-free nature. However, these devices can be complex, deliver limited throughput, and rely on sample dilution, making them challenging to deploy as routinely used tools. We are developing platforms capable of label-free separation from unmodified whole blood to rapidly fractionate blood cells or screen rare cell populations, for downstream analysis or drug screening.
Michigan Huron Room
7 May 2024
14:00

Sunitha Nagrath, Professor of Chemical Engineering and Biomedical Engineering, University of Michigan-Ann Arbor, United States of America
The Next Big Small Things: Technology Driven Approaches to Bring Extracellular Vesicles into the Clinic
Small nanoscale extracellular vesicles (EVs), known as exosomes, represent a rapidly emerging biomarker for cancer detection by liquid biopsy. Given the tiny amount of cargo carried by these nano-sized vesicles, the development of techniques that can analyze these important carriers is an active area of research in recent times. Additionally, while high in information content, the current exosomes profiling protocols are lengthy, preventing their widespread utilization and cancer diagnostics in a timely manner. Recent advances in technologies and approaches will be discussed to isolate and probe exosomes. We present the isolation of tumor derived EVs and their molecular cargo for rapid cancer diagnosis and in-depth mutation profiling.
Exhibit Hall
7 May 2024
14:30
Mid-Afternoon Coffee Break and Networking
Michigan Huron Room
7 May 2024
14:55
Session Title: Presentations based on Selected Submitted Abstracts
Michigan Huron Room
7 May 2024
15:00

Riya Aggarwal, Student Researcher, Potkay Laboratory, University of Michigan - Ann Arbor, United States of America
Enhancing the Hemocompatibility of 3D-Printable Silicone Elastomers for Artificial Lung Applications
In this study, we investigate the nonthrombogenic effects of imbuing our polydimethylsiloxane (PDMS) based 3D-printable resin with hydrophilic molecules with the goal of reducing the body’s natural coagulation response to foreign materials, coming closer to mimicking the native blood interface.
Michigan Huron Room
7 May 2024
15:30

Vivek Rajasenan, PhD Candidate, Di Carlo Laboratory, UCLA, United States of America
3D Printed Droplet and Inertial Microfluidics
Resin 3D printing is replacing conventional techniques in microfluidics manufacturing due to its prototyping speed and channel-shaping capabilities. While simple in nature, this manufacturing approach is typically limited by channel resolution (>100 microns), caused by large penetration depths in resins resulting in partially polymerized resins in embedded microchannels. Techniques aiming to address this challenge, such as resin absorbers and optical tuning, constrain material properties or require complex, custom-built printers, posing obstacles that frequently impede accessibility. Leveraging the remnant reactive groups in the resin following low-cost LCD-based SLA printing, we introduce a simple and scalable compression bonding method to create high-resolution, high-strength, and transparent microfluidic devices capable of withstanding pressures greater than 280 psi. We demonstrate shear-free step emulsifiers with sub-100-micron channels that can produce very precise droplets (<5% CV) and particles at scale. We also demonstrate a rigid inertial microfluidic device capable of focusing microparticles into single streams.
Michigan Huron Room
7 May 2024
15:45

Vivek Rajasenan, PhD Candidate, Di Carlo Laboratory, UCLA, United States of America
3D Hydrodynamic Focusing Using 3D-Printed Microfluidic Nozzles for Complex Microfluidic Fiber Fabrication
Microfibers are indispensable in various fields including bioprocessing, tissue engineering, optics, and medicine. Current methods for fabricating microfibers often rely on complex hydrodynamic and inertial shaping techniques, limiting capability and scalability. Our work presents microfiber fabrication by utilizing coaxial flow patterns enabled by low-cost, 3D printed nozzles. This approach allows for the rapid prototyping of intricate fiber structures within hours, bypassing the need for complex device fabrication protocols. Through three-dimensional hydrodynamic focusing, we achieve continuous and stable photopolymerization of monomer solutions, yielding microfibers with feature resolutions below 100 micrometers. Our method enables the production of diverse microfiber shapes, including circular, non-circular, and hollow-shell architectures, with the capability of incorporating multiple materials. Furthermore, we demonstrate the parallelization of devices to scale fiber production. These advancements have broad implications in biosensing, drug delivery, gas exchange, fiber optics, and soft robotics, enhancing capabilities across various disciplines.