
Next-Gen Technologies & Tools Driving EV Research 2025
Date: Thursday, September 11, 2025 - Friday, September 12, 2025
Location: Chicago North Shore/Skokie, Illinois
Confirmed Speakers

Brian Cunningham, Professor and Intel Alumni Endowed Chair, University of Illinois at Urbana-Champaign -- Conference Co-Chairperson

Erik Nelson, Associate Professor of Molecular and Integrative Physiology, Co-Program Lead, Cancer Center at Illinois, University of Illinois Urbana Champaign

Steve Soper, Foundation Distinguished Professor, Director, Center of BioModular Multi-Scale System for Precision Medicine, The University of Kansas

Colin Hisey, Assistant Professor, Department of Biomedical Engineering, Northwestern University

Johnny Zhuang, Business Development & Product Application Scientist, EXODUS BIO

Sven Kreutel, CEO, Particle Metrix, Inc. -- Conference Premier Sponsor

Erhard Bieberich, Professor, Department of Physiology, College of Medicine, University of Kentucky -- Conference Co-Chairperson

Stephen Boppart, Professor and Grainger Distinguished Chair in Engineering, University of Illinois Urbana-Champaign
Overview of the Conference
SelectBIO Next-Gen Technologies & Tools for EV Research Conference brings together researchers from academic institutions and companies in the Chicago North Shore/Skokie, Illinois area for a 2-day intensive event.
This event includes the following:
Scientific Presentations from Invited Speakers from Academic Institutions
Technology Spotlight Presentations from Companies Focused in the EV Space
Exhibits
Hands-on Demos by Companies Developing and Commercializing Instruments Enabling Various Aspects of EV Research
Networking Opportunities Over Lunches and Evening Reception
The goal of this event is to discuss the latest research in EVs and complement this with the latest technologies and tools enabling EV research.
Companies will showcase their products and services and engage the participants with hands-on demonstrations on their instrumentation and address questions of usage as well as run EV samples onsite to demo the products.
SelectBIO is delighted to be co-producing this event with Particle Metrix, Inc. -- Conference Premier Sponsor
We encourage participation by other companies in the EV field as a means to provide a well-balanced demo conference and to engage the conference participants with a wide spectrum of technologies, platforms and tools.
Abstract Submission for Oral Presentations & Posters
You can present your research whilst attending the conference via an oral presentation or via a poster.
Abstracts can be Submitted under the Submissions tab of this conference website.
Oral Presentation Submission Deadline: June 30, 2025
Poster Submission Deadline: August 31, 2025
Agenda Topics Covered at this Conference
Emerging Areas in EV Research
Various Platforms for the Isolation of EVs Characterization of EVs -- NTA and Beyond
Downstream Analysis of EV Cargo -- RNAs, Proteins and Lipids
Platforms for Single EV Analysis -- Flow Cytometry
Advancements in Technologies and New Disruptive Technologies in EV Research
Sponsorship and Exhibition Opportunities
Jeff Fan Exhibition Manager - SelectBIO Conferences
E-mail: Jeff@selectbioconferences.com
3 for 2 Offer on Delegate Registrations
SelectBIO are offering 3 Delegate Registrations for the price of 2 on all delegate passes. To take advantage of this offer, please contact us by email, phone or click the Contact Us button below. Looking for more than 3 Delegate Passes? Contact us for more information on our special rates for large groups.
Any questions or assistance during registration, please call us at: +1 (510) 857-4865 or e-mail us at: Contact SelectBIO
Gold Sponsors
Exhibitors
Sponsorship and Exhibition Opportunities
If you require any information about exhibiting or sponsoring at one of our events please contact Jeff Fan using the information below:
Jeff Fan, Exhibition Manager
Email: jeff@selectbioconferences.com
Telephone: +1-510-857-4865
Why exhibit at a SELECTBIO show?
Specialists: SELECTBIO doesn't organise conferences in shipping, accountancy, textiles etc. – just drug discovery and the life sciences. Many of our staff have bioscience qualifications and many years of experience. So, we speak your language and understand your needs.
Superior Customer Service: Our sales team will take care of you with specialist advice and customised packages. We don’t forget you after you sign on the bottom line either as our customer service dept. will alert you to all the things you need to think about up to and during the event itself.
Networking: Pre-Event, During and Post-Event you can communicate electronically with all other attendees either using our U-NETWORK system from your PC or via our exclusive new app
Free Lead Retrieval System: Why pay a small fortune for a third party system? SELECTBIO empower you to do this yourself with the badge scanner built into our new app using your smartphone or tablet.
Next-Gen Technologies & Tools Driving EV Research 2025 Conference Venue
SelectBIO is pleased to host this EV Conference at the following venue:
Holiday Inn and Suites Chicago - North Shore
Skokie Banquet and Conference Center
5300 W Touhy
Skokie, Illinois, 60077
USA
Telephone: +1-847-679-8900
This full service hotel north of Downtown Chicago is surrounded by shopping, attractions and dining.
Located just blocks from the Edens Expressway (Interstate 94), and equally convenient access to Interstate 90 & 294.
To make your Hotel Reservations Online:




For any hotel reservation-related issues, or if you need any help with hotel bookings, please contact:
Jeff Fan Events Manager, SelectBIO Conferences
E-mail: Jeff@selectbioconferences.com
SelectBIO has NOT authorized ANY third party company to assist in hotel bookings or reservations for the conference. Please do NOT do business with any third party companies. If in doubt, please contact Jeff Fan immediately to clarify.
Register to this conference and also enjoy the following co-located events at no extra charge.
Training Courses
If you would like to submit a proposal for an oral or poster presentation at this meeting, please fill out the form below required for your submission.
Successful applicants will be provided with all necessary information.
Abstract Content:
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Written in English
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Written in the third person
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Include title, name(s) and affiliation(s) of the authors
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Between 100 - 200 words
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Suitable for direct publication in the proceedings pack and on the website
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Related to the subject of the conference
Agenda Topics
Emerging Areas in EV Research
Various Platforms for the Isolation of EVs Characterization of EVs -- NTA and Beyond
Downstream Analysis of EV Cargo -- RNAs, Proteins and Lipids
Platforms for Single EV Analysis -- Flow Cytometry
Advancements in Technologies and New Disruptive Technologies in EV Research
Copyrights
The presenting author/person who submitted the abstract assumes full responsibility of the content of the abstract and we assume that all co-authors are aware of this content. Please note that your biography, summary and abstract may be used on this website and conference materials.
Brian Cunningham, Professor and Intel Alumni Endowed Chair, University of Illinois at Urbana-Champaign -- Conference Co-Chairperson

Brian Cunningham Biographical Sketch
Professor Cunningham has been a faculty member in the department of Electrical and Computer Engineering and the department Bioengineering at the University of Illinois at Urbana-Champaign since 2004, following a 15-year career in Industry. Prof. Cunningham’s technical focus is the utilization of photonics for biosensing in applications that include life science research, diagnostics, environmental monitoring, and pharmaceutical screening. He has over 90 issued US patents and over 200 peer reviewed journal publications. He is a Fellow of NAI, IEEE, Optica, RSC, AAAS, and AIMBE. He serves as the Director of the Center for Genomic Diagnostics at the Woese Institute for Genomic Biology, and as a Program Leader for the Cancer Center at Illinois on the topic of Cancer Measurement Technology and Data Science. In 2023, his technical contributions were recognized by Optica by the Michael S. Feld Biophotonics Award.
Colin Hisey, Assistant Professor, Department of Biomedical Engineering, Northwestern University

Colin Hisey Biographical Sketch
Dr. Colin Hisey earned B.Eng. and M.S. degrees in Chemical Engineering from the University of Dayton and a Ph.D. in Biomedical Engineering from The Ohio State University in 2018, where he developed microfluidic devices for cancer engineering applications. He then spent three years as a Postdoctoral Research Fellow at the University of Auckland in New Zealand, where he helped establish and run the Hub for Extracellular Vesicle Investigations and is now an Honorary Senior Lecturer. He returned to Ohio State in 2021 and was awarded a MOSAIC K99/R00 from NIBIB (NIH). In late 2024, he became a tenure-track Assistant Professor at Northwestern University’s Department of Biomedical Engineering and launched his independent research program. Dr. Hisey’s research combines micro-nanotechnology, extracellular vesicles, and more recently machine learning, primarily in the field of cancer engineering but also in infectious diseases, reproductive health, and neuroscience.
Erhard Bieberich, Professor, Department of Physiology, College of Medicine, University of Kentucky -- Conference Co-Chairperson

Erhard Bieberich Biographical Sketch
Our lab is interested in understanding the function of lipids, particularly the sphingolipid ceramide, in neural development and neurodegeneration. We have discovered that ceramide is enriched in membranes and compartments (ceramide-enriched compartments) that are critical for the function of primary and motile cilia in neural progenitor cells in brain development and exosomes in Alzheimer's disease. Current and future research is focused on understanding specific ceramide-protein interactions that regulate cell signaling in stem and neuroprogenitor cells, glial cells, and neurons.
1986: MS in Biochemistry, University of Cologne, Germany 1990: PhD in Biochemistry, University of Cologne, Germany 1990-1996: Post-doctoral fellow at the Department of Physiol. Chemistry, University of Bonn, Germany 1996-2000: Instructor and then Assistant Professor (1999) at the Department of Biochemistry, Virginia Commonwealth University, Richmond, VA 2000-2017: Assistant, Associate (2004), and then full Professor (2011, tenured) at the Department of Neuroscience and Regenerative Medicine, Medical College of Georgia at Augusta University, Augusta, GA 2017: Full Professor at the Department of Physiology, University of Kentucky, Lexington, GA.
Erik Nelson, Associate Professor of Molecular and Integrative Physiology, Co-Program Lead, Cancer Center at Illinois, University of Illinois Urbana Champaign

Erik Nelson Biographical Sketch
Dr. Erik Nelson is an Associate Professor of Molecular and Integrative Physiology and a co-program leader at the Cancer Center at Illinois, University of Illinois. He is an Era of Hope Scholar (Department of Defense Breast Cancer Research Program) and an Endocrine Society Laureate Awardee. Dr. Nelson is an expert in endocrinology, nuclear receptor pharmacology, cholesterol homeostasis, and cancer biology. Dr. Nelson received his PhD in comparative endocrinology from the University of Calgary, Canada where he characterized the hormonal regulation and functional significance of nuclear receptors. Mentored by Dr. Donald P. McDonnell, he pursued his postdoctoral studies in the Department of Pharmacology and Cancer Biology at Duke University School of Medicine. Here, he studied how obesity and cholesterol impact various disease pathologies including osteoporosis and breast cancer. He was also part of the team that positioned the now FDA approved Elacestrant for the treatment of metastatic breast cancer. His current research interests are in how endocrine and metabolic factors impact tumor immunology. The focus of the laboratory is on how cholesterol metabolism and homeostasis can reprogram myeloid immune cells, with the goal of developing better lifestyle and therapeutic strategies for the treatment of breast and ovarian cancers.
Johnny Zhuang, Business Development & Product Application Scientist, EXODUS BIO

Johnny Zhuang Biographical Sketch
Johnny Zhuang, a Business Development & Product Application Scientist at EXODUS BIO since March 2023, plays an important role in the development and application of the EXODUS - automatic exosome isolation system. He obtained his Bachelor of Science from Hong Kong Baptist University and his Master of Science in Biotechnology from Georgetown University. Johnny's diverse experience includes significant roles in research and product application at Charles River Laboratories, as well as in research at NOVAVAX INC and Nantomics LLC.
Stephen Boppart, Professor and Grainger Distinguished Chair in Engineering, University of Illinois Urbana-Champaign

Stephen Boppart Biographical Sketch
Dr. Stephen Boppart is a Professor and Grainger Distinguished Chair in Engineering at the University of Illinois Urbana-Champaign with appointments in the Departments of Electrical and Computer Engineering, Bioengineering, and the Carle Illinois College of Medicine. His Biophotonics Imaging Laboratory is focused on developing novel optical biomedical diagnostic and imaging technologies and translating these into clinical applications. Dr. Boppart received his Ph.D. in Medical and Electrical Engineering from MIT, his M.D. from Harvard Medical School, and specialty training in Internal Medicine. He has published over 450 invited and contributed publications, delivered over 1000 invited and contributed presentations, and has over 55 patents related to optical biomedical imaging technology. He was recognized by MIT Technology Review magazine as one of the Top 100 young innovators who will create the future, and later received the international Hans Sigrist Prize in the field of Diagnostic Laser Medicine, the IEEE Technical Achievement Award, the SPIE Biophotonics Technology Innovator Award, and recently, the Michael S. Feld Biophotonics Award from Optica, among others. Dr. Boppart has co-founded four start-up companies to commercialize and disseminate his optical technologies and was recently elected a member of the National Academy of Inventors. He is a Fellow of AAAS, IEEE, OSA, SPIE, AIMBE, BMES, and IAMBE. Dr. Boppart has been a strong advocate for the integration of engineering, technology, and medicine to advance human health and our healthcare systems. He played an active role in the visioning, launch, and growth of the first engineering-based Carle Illinois College of Medicine at the University of Illinois Urbana-Champaign, and is currently serving as the Director for the University’s Interdisciplinary Health Sciences Institute.
Steve Soper, Foundation Distinguished Professor, Director, Center of BioModular Multi-Scale System for Precision Medicine, The University of Kansas

Steve Soper Biographical Sketch
Prof. Soper (since 2016) is a Foundation Distinguished Professor in Chemistry and Mechanical Engineering at the University of Kansas. At KUMC, Prof. Soper holds an adjunct appointment in the Cancer Biology Department and is a member of the KU Cancer Center. He also holds an appointment at Ulsan National Institute of Science and Technology in Ulsan, South Korea, where he is a World Class University Professor.
As a result of his efforts, Prof. Soper has secured extramural funding totaling >$125M, has published over 245 peer-reviewed manuscripts (h index = 70; >17,000 citations); 31 book chapters and 71 peer-reviewed conference proceeding papers, and is the author of 12 patents. He is also the founder of a startup company, BioFluidica, which is marketing devices for the isolation and enumeration of liquid biopsy markers. Soper recently founded a second company, Sunflower Genomics, which is seeking to market a new DNA/RNA single-molecule sequencing platform. His list of awards includes Ralph Adams Award in Bioanalytical Chemistry, Chemical Instrumentation by the American Chemical Society, the Benedetti-Pichler Award for Microchemistry, Fellow of the AAAS, Fellow of Applied Spectroscopy, Fellow of the Royal Society of Chemistry, R&D 100 Award, Distinguished Masters Award at LSU and Outstanding Scientist/Engineer in the state of Louisiana in 2001. Finally, Prof. Soper has granted 50 PhDs and 7 MS degrees to students under his mentorship. He currently heads a group of 15 researchers.
His major discoveries include: (1) Technology for the detection of liquid biopsy markers that can manage a variety of diseases using a simple blood test (test has been demonstrated in multiple myeloma, pediatric acute lymphoblastic leukemia, acute myeloid leukemia, pancreatic, breast, colorectal, prostate, and ovarian cancers); (2) new hardware and assay for the point-of-care diagnosis of acute ischemic stroke; (3) single-molecule DNA and RNA sequencing nanotechnology; and (4) currently working on a home-test for COVID-19 infections (handheld instrument and the associated assay.
Sven Kreutel, CEO, Particle Metrix, Inc. -- Conference Premier Sponsor

Sven Kreutel Biographical Sketch
Sven Kreutel studied biology at the University of Hohenheim in Stuttgart, Germany. After his graduation in biology, he received his PhD in microbiology and protein biochemistry at the University of Hohenheim under Prof. Dr. Andreas Kuhn and Dr. Dorothee Kiefer working on the light sensing and signal transduction in photosynthetic bacteria. Since then, he worked in different sales and sales manager positions within the life science industry from clinical research over biology to nanoparticle sciences.
08:00
11 September 2025
Conference Registration
Conference Registration, Materials Pick-Up, Coffee and Networking
09:00
11 September 2025
Conference Ballroom
Chairperson Introduction

Erhard Bieberich, Professor, Department of Physiology, College of Medicine, University of Kentucky, USA -- Conference Co-Chairperson
Welcome and Introduction to the Conference by Conference Co-Chairperson
**Discussion of EV Research Themes and Topics Covered at this Conference**
09:15
11 September 2025
Conference Ballroom
Chairperson Introduction

Brian Cunningham, Professor and Intel Alumni Endowed Chair, University of Illinois at Urbana-Champaign, USA -- Conference Co-Chairperson
Welcome and Introduction to the Conference by Conference Co-Chairperson
**Discussion of EV Research Themes and Topics Covered at this Conference**
09:29
11 September 2025
Conference Ballroom
Opening Session
Session Title: Conference Opening Session and State of EV Research 2025
10:00
11 September 2025
Conference Ballroom

Stephen Boppart, Professor and Grainger Distinguished Chair in Engineering, University of Illinois Urbana-Champaign, United States of America
Visualizing and Characterizing Extracellular Vesicles In situ and In vivo Using Label-Free Multimodal Nonlinear Optical Imaging
Technological advances in optical imaging and sensing have enabled new ways to visualize and characterize the complex and dynamic processes in biology and medicine. Label-free multimodal multiphoton imaging is used to image and optically characterize physical and biomolecular properties of extracellular vesicles (EVs). Real-time imaging visualizes the spatiotemporal distribution of EVs in situ in tissue microenvironments, in biofluids, or even in vivo. Optical signatures identify cancer-associated EVs and with AI analysis, demonstrate correlations to disease aggressiveness. This platform technology is based on Simultaneous Label-free Autofluorescence Multi-harmonic (SLAM) microscopy. Co-registered images are collected from two- and three-photon excited autofluorescence intensities/lifetimes of NAD(P)H and FAD, which reflect EV and parent cell redox state. Second/third harmonic generation provided structural imaging of collagen and lipid/aqueous interfaces. Label-free imaging and characterization of EVs in cell cultures, animal models, and from tissues, serum, and urine from human breast cancer and healthy subjects was performed. Optical signatures revealed changes in EV properties based on metabolic states (redox ratios). Increased metabolic activity in human breast tumors was reflected in EV signatures from label-free images of the tissue collected intraoperatively using a portable imaging system. AI analysis of multimodal images was applied for spatial biology visualization of the tissue microenvironment and association of EVs to various cell types and vasculature. Label-free characterization of EVs from urine, serum, and tissue of human breast cancer subjects showed trends indicative of the presence and aggressiveness of the disease. Label-free multimodal nonlinear imaging/characterization of EVs represents a platform technology. With spatiotemporal imaging and single-EV resolution, new investigations into the dynamics, distribution, and trafficking of EVs is possible to elucidate biological processes and generate new optical biomarkers for clinical diagnosis and treatment monitoring.
10:30
11 September 2025
Exhibit Hall
Mid-Morning Coffee Break and Networking in the Exhibit Hall
11:00
11 September 2025
Conference Ballroom

Erik Nelson, Associate Professor of Molecular and Integrative Physiology, Co-Program Lead, Cancer Center at Illinois, University of Illinois Urbana Champaign, United States of America
A Cholesterol Metabolite Stimulates the Secretion of Pro-Cancer Extracellular Vesicles From Immune Cells
Breast cancer continues to be the second leading most cause of cancer-related mortality in women. Thus, new biological insights and therapeutic targets are required. Elevated circulating cholesterol is associated with a poor prognosis while patients taking cholesterol lowering medication (statins) have an increased recurrence free and overall survival time. We have found that while cholesterol does have effects on breast tumors, its metabolite, 27-hydroxycholesterol (27HC) is a major mediator of these effects. 27HC works in several different ways. (1) In estrogen receptor positive cancer, 27HC activates this receptor to promote proliferation. (2) 27HC works through the liver x receptor (LXR) in myeloid immune cells to suppress T cell activity. (3) 27HC induces extracellular vesicle (EV) biogenesis in myeloid cells. These EVs independently stimulate tumor growth and metastasis, in part through inducing a stem-like phenotype in cancer cells. This talk will focus on how 27HC increases EV biogenesis, and how those EVs influence tumor pathophysiology. Collectively, this work forms the mechanistic basis of how cholesterol supports tumor growth and progression.
11:30
11 September 2025
Conference Ballroom

Colin Hisey, Assistant Professor, Department of Biomedical Engineering, Northwestern University, United States of America
From Bioreactors to Biosensors: Platform Technologies for Advancing EV Research
While extracellular vesicles (EVs) have shown significant promise over the past decade in diagnostic, mechanistic, and therapeutic applications, several technical challenges exist which continue to limit their clinical translation, including their scalable production, selective isolation, and efficient characterization. In this talk, I will highlight several approaches to overcoming or mitigating these issues including EV production using commercially available bioreactors, nanoplasmonic sensors combined with machine learning to classify EVs based on their Raman spectra, and a new approach called light-induced extracellular vesicle and particle adsorption (LEVA) for micropatterning EVs at subcellular resolution in various applications. In combination, we demonstrate the incredible potential of applying micro-nanofabrication strategies to create platform technologies that will advance EV research.
12:00
11 September 2025
Conference Ballroom
Gold Sponsor

Johnny Zhuang, Business Development & Product Application Scientist, EXODUS BIO, United States of America
High-Efficiency Isolation of Exosomes and Its Application in Diagnosis and Treatment
Introducing EXODUS, our innovative automatic exosome isolation system, which employs advanced techniques such as periodic negative pressure oscillation and double-coupled harmonic oscillation. This unique integration ensures the high yield and purity of label-free exosomes. Widely utilized in research for disease biomarker discovery, EXODUS also offers a large-scale model, the EXODUS-T, specifically designed to cater to industrial production demands.
12:30
11 September 2025
Exhibit Hall
Networking Lunch: Meet Exhibitors and Engage with Colleagues