
Space Summit West 2025
Date: Thursday, November 20, 2025 - Friday, November 21, 2025
Location: VOCO Hotel, Laguna Hills, California
Confirmed Speakers

Anand “Sunny” Narayanan, Research Faculty, Florida State University

Kristin Kopperud, Aerospace Industry Professional -- Conference Chairperson

Meenal Datta, Assistant Professor, Department of Aerospace and Mechanical Engineering, University of Notre Dame

Munmun Chattopadhyay, Associate Professor, Texas Tech University Health Sciences Center at El Paso

Stefanie Countryman, Director, BioServe Space Technologies

Arun Sharma, Associate Professor, Cedars-Sinai Medical Center

Liz Warren, ISS Associate Chief Scientist

Melanie Coathup, Professor of Medicine and Lead, Biionix Cluster, University of Central Florida, Florida Space Institute

Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham

Yupeng Chen, Associate Professor, University of Connecticut

Chunhui Xu, Professor in the Department of Pediatrics, Emory University School of Medicine

Mari Anne Snow, CEO and Co-Founder, Eascra Biotech

Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory (CASIS)

Shelby Giza, Director of Business, Applications at Space Tango
Overview of the Conference
Space Summit West 2025 brings together researchers who have sent research payloads aboard the international space station (ISS) as well as researchers seeking to send their research into microgravity on-board the ISS.
Additionally, the impact of the private space stations coming online in low earth orbit (LEO) will be assessed from the standpoint of pricing and access to researchers.
The conference is a follow-on from the successful Space Summit 2025 held in May 2025 in Miami, Florida.
Speakers and Delegates are composed primarily of researchers involved in various disciplines that are amenable to LEO such as Organs-on-Chips in Space, Tissue-Chips, Organoids, 3D-Printing, Flow Chemistry-Space Chemistry, amongst others.
Additionally, platform and infrastructure providers who are critical in providing the correct form factor as well as telemetry on-board station will be present to provide practical guidance to researchers seeking LEO for their research.
SelectBIO is honored to welcome Dr. Kristin Kopperud -- Former Scientific Director of the International Space Station US National Laboratory (ISS-NL) as Conference Chairperson.
Abstract Submission for Oral Presentations and Posters
Agenda Topics Covered at this Conference
You can also present your research in an oral presentation or on a poster while attending the meeting. Submit an abstract for consideration under the Submissions Tab of this Conference Website
Oral Presentation Abstract Submission Deadline: September 30, 2025
Poster Presentation Abstract Submission Deadline: November 10, 2025
- • 3D-Bioprinting in Orbit
• 3D-Organoid Models for Disease in Microgravity Conditions
• Effect of Microgravity on Drug Responses
• Flow Chemistry - Chemistry in Space
• Organs-on-Chips as a Platform for Studying Effects of Microgravity on Human Physiology
• Tissue Chips in Space NIH/NCATS-ISS US National Laboratory Projects
• Research Projects in Low Earth Orbit (LEO)
• Private Space Stations offering Commercial Access to LEO for Research, Development and Manufacturing
• Platform Providers Offering Access to LEO for Scientific Research Projects
Sponsorship and Exhibition Opportunities
3 for 2 Offer on Delegate Registrations
SelectBIO are offering 3 Delegate Registrations for the price of 2 on all delegate passes. To take advantage of this offer, please contact us by email, phone or click the Contact Us button below. Looking for more than 3 Delegate Passes? Contact us for more information on our special rates for large groups.
Any questions or assistance during registration, please call us at: +1 (510) 857-4865 or e-mail us at: Contact SelectBIO
Gold Sponsors
Exhibitors
Sponsorship and Exhibition Opportunities
If you require any information about exhibiting or sponsoring at one of our events please contactJeff Fan using the information below:
Jeff Fan
Exhibition Manager - SelectBIO Conferences
Why Exhibit-Sponsor at a SelectBIO Conference?
Specialists: SelectBIO doesn't organize conferences in shipping, accountancy, textiles etc. – just drug discovery and the life sciences. Many of our staff have bioscience qualifications and many years of experience. So, we speak your language and understand your needs.
Superior Customer Service: Our sales team will take care of you with specialist advice and customized packages. We don’t forget you after you sign on the bottom line either as our customer service dept. will alert you to all the things you need to think about up to and during the event itself.
Space Summit West 2025 Conference Venue
SelectBIO is pleased to host this Space Summit West 2025 Conference at VOCO Laguna Hills: An IHG Hotel -- Laguna Hills, California.
VOCO Laguna Hills
25205 La Paz Road
Laguna Hills, California 92653, USA
This hotel in Southern California is easily accessible from Los Angeles and San Diego via Interstate-5 (I-5).
The nearest airport is: John Wayne Airport (SNA) - 13.7 miles from the hotel.
From Los Angeles International Airport (LAX) - the hotel is 52.9 miles.
The hotel is within a short drive of Disneyland and Legoland California, as well as Laguna Beach, Newport Beach, as well as shopping and dining at South Coast Plaza in Costa Mesa.
All conference sessions, exhibition as well as networking reception will be held in the Garnet Gallery at VOCO Laguna Hills.
SelectBIO has negotiated discounted hotel room pricing for conference attendees at VOCO Laguna Hills.
To make your Hotel Reservations Online: Click the Button Below to Open the Hotel Booking Website This will provide a SelectBIO discounted rate for booking hotel rooms.




For any hotel reservation-related issues, or if you need any help with hotel bookings, please contact:
Jeff Fan
Events Manager, SelectBIO
E-mail: Jeff@selectbioconferences.com
SelectBIO has NOT authorized ANY third party company to assist in hotel bookings or reservations for the conference. Please do NOT do business with any third party companies. If in doubt, please contact Jeff Fan immediately to clarify.
Register to this conference and also enjoy the following co-located events at no extra charge.
Training Courses
If you would like to submit a proposal for an oral or poster presentation at this meeting, please fill out the form below required for your submission.
Successful applicants will be provided with all necessary information.
Abstract Content:
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Written in English
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Written in the third person
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Include title, name(s) and affiliation(s) of the authors
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Between 100 - 200 words
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Suitable for direct publication in the proceedings pack and on the website
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Related to the subject of the conference
Agenda Topics
- • 3D-Bioprinting in Orbit
• 3D-Organoid Models for Disease in Microgravity Conditions
• Effect of Microgravity on Drug Responses
• Flow Chemistry - Chemistry in Space
• Organs-on-Chips as a Platform for Studying Effects of Microgravity on Human Physiology
• Tissue Chips in Space NIH/NCATS-ISS US National Laboratory Projects
• Research Projects in Low Earth Orbit (LEO)
• Private Space Stations offering Commercial Access to LEO for Research, Development and Manufacturing
• Platform Providers Offering Access to LEO for Scientific Research Projects
Copyrights
The presenting author/person who submitted the abstract assumes full responsibility of the content of the abstract and we assume that all co-authors are aware of this content. Please note that your biography, summary and abstract may be used on this website and conference materials.
Anand “Sunny” Narayanan, Research Faculty, Florida State University

Anand “Sunny” Narayanan Biographical Sketch
Dr. Anand “Sunny” Narayanan is currently a Research Professor at Florida State University. Sunny holds a Ph.D. from Texas A&M University in Medical and Space Physiology, and B.S. degrees from West Virginia University in Mechanical Engineering and Biology. Sunny took his first professional steps with NASA supporting systems engineering computational projects at the Katherine Johnson Independent Verification and Validation Facility, completing team-based design-build-fly projects through NASA’s Microgravity University program, and conducting nanotechnology biomedical research as a Ronald E. McNair Scholar. He continued his academic steps at Texas A&M University, supported by the National Space Biomedical Research Institute for his doctorate to study physiological adaptations of astronauts during their journey in space. While his research focus was of the lymphatic and immune systems’ adaptations to spaceflight and clinical conditions, Sunny also led and supported interdisciplinary projects on topics including musculoskeletal, digestive, and cerebral science. His doctoral work also involved opportunities at Brookhaven National Labs, International Space Station spaceflight biomedical projects (Rodent Research-3, 9, and 18 and Rodent Research Reference Mission-2), National Institutes of Health, and NASA Kennedy and Johnson Space Centers. Now as a Research Professor, he continues his support of NASA’s space program, leading and supporting multiple biomedical studies investigating the physiological effects of deep space radiation, Lunar, and Martian gravity, relevant to our human space exploration goals as we return to the Moon and beyond through the Artemis program.
Arun Sharma, Associate Professor, Cedars-Sinai Medical Center

Arun Sharma Biographical Sketch
Dr. Arun Sharma, PhD is a stem cell biologist focusing on cardiovascular biology and space biosciences. He is an associate professor at Cedars-Sinai and is affiliated with the Board of Governors Regenerative Medicine Institute, the Smidt Heart Institute, the Cancer Institute, and the Department of Biomedical Sciences.
Research in the Sharma laboratory focuses on the applications of human induced pluripotent stem cells (hiPSCs) for modeling cardiovascular diseases outside of the body (in-vitro). The lab utilizes cutting-edge technologies including hiPSCs, genome editing, cardiac organ-on-chips, and 3D cardiac spheroids/organoids to understand the molecular mechanisms driving cardiovascular disease and heart development. For example, the Sharma laboratory employs hiPSC-derived cardiomyocytes (personalized, beating heart muscle cells) to develop novel ways to alleviate the cardiovascular damage caused by cancer drugs. The lab also studies the developmental mechanisms underlying congenital heart disease, as well as examines the impact of infections on the cardiovascular system, such as in the setting of COVID-19.
Sharma also has a unique background and interest in the space biosciences and investigates means by which stem cell biology can intersect with this emerging field. In 2016, Dr. Sharma led a project that sent human stem cell-derived heart cells to the International Space Station to study the effects of microgravity on human heart function, which was the first long-duration cell culture experiment in space. He remains an internationally-recognized leader in the space biosciences field, and his laboratory studies means of harnessing microgravity to manufacture unique biomaterials.
Sharma has published articles in leading scientific journals such as Science, Nature Biotechnology, Science Translational Medicine, Circulation Research, Nature Reviews, Stem Cell Reports, and Cell Stem Cell. His research has been featured in major news outlets such as Forbes Magazine, Newsweek, Science Magazine, and the Wall Street Journal. He has received numerous awards for his work, including the Forbes 30 Under 30 in Science, STAT Wunderkinds, Sartorius & Science Award in Regenerative Medicine, the American Heart Association Career Development Award, the Compelling Results Award from NASA, and the Donna and Jesse Garber Award for Cancer Research.
Chunhui Xu, Professor in the Department of Pediatrics, Emory University School of Medicine

Chunhui Xu Biographical Sketch
Chunhui Xu, PhD, is a Professor in the Department of Pediatrics, Emory University School of Medicine. Dr. Xu has extensive research experience on stem cells and heart cell development. Her research is focusing on heart cells derived from human pluripotent stem cells (hPSCs), which hold promise for cell therapy, disease modeling, and drug discovery. Her group has made significant contribution to the field of hPSCs. Several of their publications have been identified as a hot paper or among the most highly cited publications in the field of hPSCs. She is an inventor or co-inventor of 18 issued US patents, and her publications have been cited more than 12,000 times according to Google Scholar. Her research has been funded by NCI, NHLBI, NIAAA, NSF, CASIS, GA Research Alliance, AHA, and HESI/FDA. Her spaceflight experiment was called as a significant step for next-generation space research by the International Space Station National Laboratory, and featured by the ISS National Lab, NSF, NASA, CNN, and Chemical & Engineering News.
Kristin Kopperud, Aerospace Industry Professional -- Conference Chairperson

Kristin Kopperud Biographical Sketch
Dr. Kristin Kopperud is an aerospace industry veteran with experience in operations project management and expertise in tissue engineering and regenerative medicine experiments in microgravity. Her previous position at the Center for the Advancement of Science in Space, Inc. (CASIS), which manages the International Space Station (ISS) National Laboratory, as Science Program Director of Biological Sciences in the Research and Innovation department included focus areas in biomanufacturing, in-space production applications, and rodent research. Dr. Kopperud received BS degrees in Biotechnology and Biology from the University of Kentucky. She earned her PhD in Biological Sciences from Florida Institute of Technology in Melbourne, FL studying circadian rhythms in the Atlantic tarpon. While she moved to Florida to pursue a career in marine biology, she was captivated by the space culture that was inescapable on the Space Coast. During graduate school, she taught undergraduate laboratory sections of Mammalian Physiology and Biology and was recruited to serve as a Research Support Scientist for several ISS National Lab-sponsored Rodent Research missions, serving as a surrogate for the crew on the ISS.
Liz Warren, ISS Associate Chief Scientist

Liz Warren Biographical Sketch
Liz Warren, Ph.D. is the International Space Station Associate Chief Scientist. She has a wealth of experience from over 25 years of spaceflight research involvement, including space shuttle missions, the Mir space station, and ISS. Liz was born and raised in the San Francisco Bay Area, and attended the University of California at Davis for both her undergraduate and doctorate degrees in physiology. For her doctoral work, she investigated the effects of gravity as a continuum on energy balance in rats. She completed post-doctoral work in cancer biology at the San Francisco Veterans Affairs Laboratory of Cell Growth and in the Neuroscience Laboratory at NASA’s Johnson Space Center. Liz most recently served as KBR’s Chief Scientist for NASA’s Human Health and Performance contract. Prior to that, Liz was the Director of Research Development for Blue Origin’s Orbital Reef commercial space station. She has also served at the ISS National Lab and in NASA’s Mission Control Center. Liz is a passionate science communicator and advocate for STEM.
Mari Anne Snow, CEO and Co-Founder, Eascra Biotech

Mari Anne Snow Biographical Sketch
Mari Anne Snow is the CEO and co-founder of Eascra Biotech, an innovative nanomedicine startup based in Worcester, Massachusetts. Under her leadership, Eascra is pioneering precision therapeutic delivery solutions for challenging tissues, including articular cartilage, kidneys, and ECM-rich solid tumors. Their proprietary Janus base nanoparticles (JBNps) are DNA-inspired synthetic molecules that encapsulate therapeutic agents, maintaining room temperature stability and extended bioactivity. In collaboration with NASA, the ISS National Lab, Axiom Space, and other commercial space companies, Mari Anne and her team are leveraging low Earth orbit to accelerate the development of advanced therapeutics. The Eascra team successfully completed five missions in microgravity in 24 months. Before founding Eascra, Mari Anne established the Remote Nation Institute, focusing on optimizing productivity in remote and dispersed organizations. Mari Anne is the author of "The Remote Work Handbook," a comprehensive guide to building effective remote team operating models. With extensive expertise in business strategy, entrepreneurship, change management, organizational development, and remote team leadership, she is a recognized authority in her field.
Meenal Datta, Assistant Professor, Department of Aerospace and Mechanical Engineering, University of Notre Dame

Meenal Datta Biographical Sketch
Meenal Datta is an assistant professor in the Department of Aerospace and Mechanical Engineering at the University of Notre Dame, with a concurrent appointment in the Department of Chemical and Biomolecular Engineering. Prof. Datta received her Ph.D. in chemical and biological engineering from Tufts University in 2018, after which she completed a postdoctoral fellowship at Harvard Medical School and Massachusetts General Hospital, before starting her faculty position in 2021. Her research focuses on deciphering the atypical tumor microenvironment that drives disease progression and treatment resistance in incurable cancers. By understanding and overcoming the biological, chemical, electrical, and mechanical abnormalities found in solid tumors, new therapeutic approaches can be discovered.
Prof. Datta specializes in multidisciplinary and mechanism-based preclinical research that has the potential to be rapidly translated to improve treatment approaches in the clinic. She has spent her time as a researcher deciphering and reprogramming abnormal tissue microenvironments that are present in a variety of diseases ranging from virulent tuberculosis to benign schwannoma to deadly glioblastoma that, surprisingly, share unifying features: abnormal blood vessels, abundant extracellular matrix, immunosuppression, and mechanopathologies. During her Ph.D., Dr. Datta normalized the aberrant blood vasculature found in pulmonary tuberculosis granulomas to improve drug delivery. In her postdoctoral training, Dr. Datta re-engineered the immunosuppressive brain tumor microenvironment to improve glioblastoma response to immunotherapy.
As the director of the Tumor Immune Microenvironment & Mechanics (TIME) Lab at Notre Dame (https://timelab.nd.edu), Prof. Datta’s research group applies engineering fundamentals and problem-solving approaches to explore immunomechanics and mechano-immunology in health and disease and to discover novel biophysical mechanisms that can be targeted therapeutically to enhance treatment outcomes in cancer and other conditions. Prof. Datta’s lab also conducts science-in-space experiments on the International Space Station (ISS) to test novel modeling and treatment approaches on cancer avatars in microgravity.
Prof. Datta has received numerous awards in support of her research including a National Heart, Lung, and Blood Institute F31 predoctoral fellowship (2016), a postdoctoral fellowship from the American Association of Cancer Research (2019), a National Cancer Institute K22 career transition award (2021), a junior faculty award from the Oak Ridge Associated Universities (2022), a National Institute of General Medical Sciences R35 award for early-stage investigators (2023), and an AFOSR Young Investigator Program award (2025). Dr. Datta’s in-space research on the ISS is supported by grants from NSF/CASIS Tissue Engineering and Mechanobiology (2024) and AFOSR Space Biosciences (2024, 2025). In 2024, Prof. Datta was awarded the Young Innovator Award in Cellular and Molecular Bioengineering from the Biomedical Engineering Society (BMES). In fall 2025, Prof. Datta will be awarded the Rising Star of Mechanical Engineering Award from the American Society of Mechanical Engineers (ASME), and the Rita Schaffer Young Investigator Award from BMES.
Melanie Coathup, Professor of Medicine and Lead, Biionix Cluster, University of Central Florida, Florida Space Institute

Melanie Coathup Biographical Sketch
Dr. Coathup is a Professor of Medicine at the Department of Medicine, College of Medicine, University of Central Florida. She is also Lead of the Biionix (Bionic Implants, Materials, & Interfaces) Cluster and a member of the Florida Space Institute, and Stephen W. Hawking Center for Microgravity Research and Education. Dr. Coathup obtained her PhD from University College London (UCL), UK, and later became Head of the Center for Tissue and Cell Research and Women in Science lead at UCL. In 2023, Dr. Coathup was inducted as a Fellow of the American Institute of Medical and Biological Engineering. Dr. Coathup’s research is focused on interdisciplinary-based innovation with the view of applying scientific discovery to improve the treatment and care of people. Her research focuses on developing novel antibacterial products, as well as advancing biomaterials, and small molecule therapeutics that boost bone repair when under challenging and complex physiological conditions. This includes aging, infection, ionizing radiation-induced injury, and bone health when in space.
Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory (CASIS)

Mike Roberts Biographical Sketch
Michael S. Roberts, PhD is the Chief Scientific Officer of the ISS National Laboratory, managed by the Center for the Advancement of Science in Space, Inc. (CASIS). Before joining CASIS, Michael worked as a principal investigator and research group lead in the NASA Advanced Life Support program at the Kennedy Space Center. Prior to arriving at NASA -KSC in 1999, Michael completed an undergraduate degree in biology at Maryville College, a doctorate in microbiology at Wesleyan University and post-doctoral research at the Center for Microbial Ecology at Michigan State University and the RIKEN Institute in Wako-shi, Japan.
Munmun Chattopadhyay, Associate Professor, Texas Tech University Health Sciences Center at El Paso

Munmun Chattopadhyay Biographical Sketch
Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham

Palaniappan Sethu Biographical Sketch
Dr. Palaniappan Sethu is a Biomedical Engineer by training with a PhD from the University of Michigan where he developed new polymer based lab-on-a-chip technologies for genomic and proteomic assays. Dr. Sethu completed his postdoctoral training at the Center for Engineering in Medicine at Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital working on label-free approaches to isolate leukocyte sub-populations from whole blood. After spending the 1st 7 years of his career at the University of Louisville, he is currently a Professor of Medicine and Biomedical Engineering within the Division of Cardiovascular Disease at the University of Alabama-Birmingham. Dr. Sethu also serve as the Section Chief for Basic and Translational Sciences within the Division of Cardiovascular Diseases and as the Program Director for the Engineering Education in Medicine Program within the Department of Biomedical Engineering.
Shelby Giza, Director of Business, Applications at Space Tango

Shelby Giza Biographical Sketch
Shelby Giza is the Director of Business Development for Applications at Space Tango, where she aligns corporate objectives with groundbreaking opportunities in health and technology for space-based research and manufacturing. Shelby bridges strategic vision with tactical implementation, fostering seamless collaboration among internal teams and external partners. Her leadership in advancing best practices for the ideation and production of patient therapeutics in space is instrumental in shaping a thriving low-Earth orbit economy. Working closely with research institutions, industry pioneers, and government stakeholders, Shelby drives partnerships that unlock new opportunities, expanding the space-based science and manufacturing solutions market.
With over 20 years of research experience centered on translational medicine, Shelby delivers evidence-based insights that ensure the design and development of advanced hardware and facilities tailored to the diverse needs of scientific ventures. She has played a pivotal role in the R&D of groundbreaking therapeutics, including NIO752 (currently in multiple Phase I trials for Progressive Supranuclear Palsy and Alzheimer’s), Beovu® (approved in 2019 for Neovascular Age-related Macular Degeneration and Diabetic Macular Edema), and the SYNERGY™ Drug-Eluting Stent (approved in 2015). Shelby’s contributions to innovation extend to mRNA vaccine technology, where she participated in the DARPA ADEPT-PROTECT program at Novartis years before the COVID-19 pandemic. She also brings International Space Station (ISS) user experience, having supported the development of a 3D human muscle tissue chip in collaboration with Space Tango and the Malany Lab at the University of Florida, which flew aboard SpaceX CRS-21.
Stefanie Countryman, Director, BioServe Space Technologies

Stefanie Countryman Biographical Sketch
Ms. Stefanie Countryman is the Director of BioServe Space Technologies and a Research Associate within the Ann and HJ Smead Aerospace Engineering and Science Department at the University of Colorado Boulder. Ms. Countryman has worked for BioServe for over 25 years. As Director, she leads a wide variety of activities including oversight of BioServe’s portfolio of space flight research and engineering projects. Ms. Countryman has been involved in or directly responsible for over 70 space life science experiments and hardware development projects ranging from the simple to the very complex. She is an expert in the process for developing, launching and operating life science experiments in space.
Yupeng Chen, Associate Professor, University of Connecticut, United States of America

Yupeng Chen Biographical Sketch
Dr. Yupeng Chen is an Associate Professor in the Department of Biomedical Engineering at the University of Connecticut. Holding both an M.Sc. and a Ph.D. in biomedical engineering and chemistry from Brown University, Dr. Chen's long-term research interest lies in the design and development of DNA-inspired Janus base nanomaterials for regenerative engineering applications. He holds 11 US patents and 14 international patents in Janus base nanotechnology, some of which have been successfully licensed to industry partners. Dr. Chen has authored one book, 11 book chapters, and 74 peer-reviewed publications, and he and his lab have delivered 127 conference presentations and invited talks. His achievements have been recognized with the Faculty Early Career Development (CAREER) award from NSF, the discovery award from DOD, and the New Investigator Recognition Awards from the Orthopaedic Research Society. Elected as a senior member of the National Academy of Inventors (NAI) and a member of the Connecticut Academy of Science and Engineering (CASE) in recognition of his efforts to translate scientific breakthroughs into practical applications, Dr. Chen has secured many competitive federal research grants from agencies such as NIH, NSF, NASA, DOD, and the International Space Station (ISS) National Lab.
08:00
20 November 2025
Garnet Gallery, VOCO Hotel
Participants Check-In
Conference Registration, Materials Pick-Up, Coffee and Continental Breakfast
08:59
20 November 2025
Garnet Gallery, VOCO Hotel
Session Title: Conference Opening Session
09:00
20 November 2025
Garnet Gallery, VOCO Hotel

Kristin Kopperud, Aerospace Industry Professional -- Conference Chairperson
Welcome and Introduction by Conference Chairperson
**Current Trends in Low Earth Orbit (LEO) Research and Commercialization**
09:30
20 November 2025
Garnet Gallery, VOCO Hotel

Melanie Coathup, Professor of Medicine and Lead, Biionix Cluster, University of Central Florida, Florida Space Institute, United States of America
Preventing Radiation- and Microgravity-Induced Injury: A Novel Countermeasure to Protect Bone
Musculoskeletal atrophy has important implications for astronaut health. Due to the extended time in near weightlessness during prolonged spaceflight beyond low-Earth orbit, together with the increased exposure to high energy radiation, the development of novel strategies that are effective in preventing and treating bone atrophy are ongoing. The toxicity to tissue occurs in part, through the generation of excess reactive oxygen species (ROS) causing genomic instability/damage, the release of proinflammatory cytokines, chronic inflammation, apoptosis, senescence, metabolic dysfunction, adipogenesis, and bone loss and fragility. In this presentation, two novel radioprotectors will be discussed. Firstly, non-toxic cerium oxide nanoparticles (CeONPs) engineered to possess a higher fraction of trivalent (Ce3+) surface sites, are shown to neutralize ROS and mitigate radiation- and unloading-induced damage to bone architecture and strength in vivo. Preliminary results also show therapeutic efficacy to macrophages when exposed to a combination of simulated microgravity and gamma irradiation. Second, the aminopropyl carbazole, P7C3, also protects against radiation- and unloading-induced bone atrophy in vivo. Finally, and due to their synergistic and additive multifunctional mechanisms, combining CeONP-P7C3 delivers a superior treatment when tested as a radiomitigator. Ultimately, we aim to develop a protective and therapeutic radio-countermeasure that will safeguard crew members during exploration missions to the Moon and Mars, as well as supporting bone health on Earth.
10:00
20 November 2025
Garnet Gallery, VOCO Hotel

Chunhui Xu, Professor in the Department of Pediatrics, Emory University School of Medicine, United States of America
Title to be Confirmed
10:30
20 November 2025
Garnet Gallery, VOCO Hotel
Mid-Morning Coffee Break and Networking
11:00
20 November 2025
Garnet Gallery, VOCO Hotel

Stefanie Countryman, Director, BioServe Space Technologies, United States of America
BioServe Space Technologies: Support for LEO and Beyond Research and Technology Development
This presentation will discuss the process for supporting life science research on board the ISS and other platforms. The presentation will cover translation of ground-based research to space-based research, hardware development and support and the overall process for successfully designing and conducting research in a microgravity environment.
11:30
20 November 2025
Garnet Gallery, VOCO Hotel

Meenal Datta, Assistant Professor, Department of Aerospace and Mechanical Engineering, University of Notre Dame, United States of America
Growing and Drugging Brain Tumor Organoids in Space
Microgravity offers key advantages for accelerated human disease modeling and therapeutic development compared to on-ground activities. Here, I will present our ongoing to efforts to grow and treat glioblastoma organoids in space, including results from prior missions to the ISS, and our upcoming plans for CLD activities.
12:00
20 November 2025
Garnet Gallery, VOCO Hotel
Networking Lunch -- Engage with Colleagues and Network
14:00
20 November 2025
Garnet Gallery, VOCO Hotel

Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham, United States of America
Streptococcus Pneumoniae (Spn) Infection of Cardiac Tissue in Space
There is evidence that the space environment enhances bacterial virulence, increases proliferation and promotes biofilm formation, potentially leading to more severe infection. Spn is a Gram-positive bacterium and the leading cause of community-acquired pneumonia; it is responsible for as many as 40% of all cases. There is strong evidence indicates that during severe community-acquired pneumonia, Spn gains access to and causes long-lasting damage in vital organs such as the heart, where Spn is now recognized to kill cardiomyocytes, form microlesions (biofilms within the cardiac tissue), impair heart function, and, in surviving animals, prime permanent cardiac scarring and impaired contractility. This talk will focus on the unique opportunity to leverage the space environment, which promotes cardiac tissue atrophy, enhances bacterial virulence and decreases susceptibility of bacteria to antimicrobial treatment to create an accelerated and more severe model of Spn infection of cardiac tissue. By exacerbating the infection process, we will amplify the molecular changes (gene expression, soluble factor production) involved in critical events that promote microlesion formation and enhance Spn virulence to understand molecular mechanisms and identify therapeutic targets for early intervention to prevent adverse cardiac events.
14:30
20 November 2025
Garnet Gallery, VOCO Hotel

Munmun Chattopadhyay, Associate Professor, Foster School of Medicine, Texas Tech University Health Sciences Center at El Paso, United States of America
Effects of Microgravity on 2D Cardiac Hetero-Cellular Cultures in Space
Microgravity exposure during prolonged space mission has been associated with debilitating cardiac health, resulting in reduction in tissue mass and decline in heart function. Cardiomyopathy, the condition that affects the heart muscle, is also an increasingly important health issue due to prolonged exposure to stress and hyperglycemia even under earth’s gravity. We established a cell- based model system to study the resultant effects of microgravity on hetero-cellular cardiac cell units and compared that with ground-based conditions that are well-known to induce atrophy. The hetero-cellular cardiac cell units were compared between 7-day microgravity exposure and 21-day microgravity exposure for stress related markers. Ground control study at 21-day demonstrated a large number of hetero-cellular coupling compared to 21-day microgravity exposure. We compared the ground control with ISS post-experimental data by the ELISA study to demonstrate the release of a number of injury and stress mediators in the culture media samples from 7-day and 21-day microgravity exposure. The data from this study indicates an impairment in the signal transduction pathways after exposure to microgravity.
15:00
20 November 2025
Garnet Gallery, VOCO Hotel
Keynote Presentation

Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory (CASIS), United States of America
Models and Outcomes of Public-Private Partnerships on the International Space Station National Lab
Research in low Earth orbit not only enables exploration, but it also accelerates scientific discovery for the translation of observations into applications for humanity that improve health outcomes on Earth, fuels innovation in manufacturing and in materials science, and creates economic value for the nation.
15:30
20 November 2025
Garnet Gallery, VOCO Hotel
Mid-Afternoon Coffee Break and Networking
16:00
20 November 2025
Garnet Gallery, VOCO Hotel
Keynote Presentation

Liz Warren, ISS Associate Chief Scientist, United States of America
International Space Station: Building on 25 Years in Orbit to Future Commercial LEO Destinations
16:30
20 November 2025
Garnet Gallery, VOCO Hotel

Shelby Giza, Director of Business, Applications at Space Tango, United States of America
Unearthing Answers: Advanced, Autonomous Biomedical Research Platforms in Microgravity
Space Tango is a recognized leader in automated R&D and manufacturing systems in low-Earth orbit, providing partners with autonomous systems integrated into the International Space Station National Laboratory with minimal astronaut intervention. Space Tango's CubeLab systems have demonstrated successful flight heritage on over 40 missions, with nearly 300 physical and life science experiments conducted on the ISS, setting the industry standard for autonomous experimentation. CubeLabs integrate multiple subsystems supporting biomedical research, including Science Interface Systems, Thermal Management, Fluid Conveyance, and Fluid Routing, with imaging capabilities through Three-Axis Microscope Systems.
Building on this proven foundation, Space Tango's latest platform, Studio, represents an evolution in automated biomedical research capabilities. This two-locker volume platform features advanced robotic capabilities for precise fluidic manipulation and sample handling within sterile environments, critical for life science applications. Studio incorporates high-precision robotic arms with interchangeable end effectors tailored for biomedical workflows, enhanced imaging capabilities, and fully customizable experimental protocols with live on-orbit updates. These automated biomedical research platforms enhance access to orbital investigations in cell culture, tissue engineering, and related life science applications across the International Space Station, future commercial space stations, and free-flying platforms.
17:00
20 November 2025
Garnet Gallery, VOCO Hotel
Panel Discussion
17:45
20 November 2025
Garnet Gallery, VOCO Hotel
Networking over Beer and Wine
18:45
20 November 2025
Close of Day 1 of the Conference
08:00
21 November 2025
Garnet Gallery, VOCO Hotel
Morning Coffee and Pastries
09:00
21 November 2025
Garnet Gallery, VOCO Hotel

Kristin Kopperud, Conference Chairperson
Recap of Day 1 and Key Topics to be Addressed on Day 2 of Space Summit West 2025
09:15
21 November 2025
Garnet Gallery, VOCO Hotel

Anand “Sunny” Narayanan, Research Faculty, Florida State University, United States of America
Spaceflight and Biomedical Adaptations of the Cardiovascular System: Our Journey to-date, and Next Steps with our Artemis Program
Our research of astronauts has shown various adaptations from their travels through space. From the perspective of the cardiovascular system, we have observed fluid shift adaptations, changes in cardiovascular structure and function, and various biological adaptations that we speculate is related due from cardiovascular adaptations. With this presentation, I will highlight the research of spaceflight cardiovascular adaptations to-date, as it relates with on-going studies in our lab, also with support from the International Space Station National Lab, and next steps with our Artemis program and future areas of research relevant to cardiovascular adaptations in space and additional areas.